Within the last few years a well visible trend for shift of biotechnological centers to Central-East Europe is observed due to economical background and exisiting crysis. This tendency is supportive for small biotechnological companies that number is increasing in the country. In Poland international branches of biotechnological and pharmaceutical concerns with biotechnological projects more frequently are developed than previously. Their characteristics is mainly multidisciplinary in biotechnological area. This paper is a short review on biotechnological market in Poland.