Simultaneous intracellular redox potential and pH measurements in live cells using SERS nanosensors

Bibliographic description

punktacja MEiN [2015 A]: 40

title:	Simultaneous intracellular redox potential and pH measurements in live cells using SERS nanosensors
author:	Jamieson Lauren E., Jaworska Aleksandra , Jang Jiang, Barańska Małgorzata , Campbell Colin J., Harrison David J.
journal title:	Analyst
volume:	140
issue:	7
date of publication :	2015
pages:	2330-2335
ISSN:	0003-2654
eISSN:	1364-5528
DOI:	10.1039/c4an02365j
URL:	https://pubs.rsc.org/en/content/articlepdf/2015/an/c4an02365j
date accessed:	2019-02-18
language:	English
journal language:	English
abstract in English:	Intracellular redox potential is a highly regulated cellular characteristic and is critically involved in main- taining cellular health and function. The dysregulation of redox potential can result in the initiation and progression of numerous diseases. Redox potential is determined by the balance of oxidants and reduc- tants in the cell and also by pH. For this reason a technique for quantitative measurement of intracellular redox potential and pH is highly desirable. In this paper we demonstrate how surface enhanced Raman scattering (SERS) nanosensors can be used for multiplexed measurement of both pH and redox potential in live single cells.
affiliation:	Wydział Chemii : Zakład Fizyki Chemicznej, Pion Rektora : Jagiellońskie Centrum Rozwoju Leków
type:	journal article
subtype:	academic paper