In the treatment of lifestyle diseases, including
metabolic syndrome and type 2 diabetes, it is important to
lower body mass and fat tissue, and consequently, to increase
insulin-sensitivity. Unfortunately, it often happens that low-
energy diet which would lower overweight is not observed
and, thus, it does not bring the expected effects. This paper
discusses the influence of three diets
—
control, high-fructose,
and high-fatty diet
—
on absorption of energy from food in
order to transform it into body mass. The kJ/g ratio which
describes this process has been calculated. In the tested diets,
the addition of fructose (79.13±2.47 kJ/g) or fat (82.48±
2.28 kJ/g) results in higher transformation of energy into body
mass than in the case of control diet (89.60±1.86 kJ/g). The
addition of Na[VO(O
2
)
2
(4,4
′
-Me
2
-2,2
′
-bpy)]
•
8H
2
O (where
4,4
′
-Me
2
-2,2
′
-bpy=4,4
′
-dimethyl-2,2
′
-bipyridine) results in sta-
tistical increase of that ratio: fruct
ose diet (86.88±0.44 kJ/g), fat diet (104.68±3.01 kJ/g), and control diet (115.98±0.56 kJ/g),
respectively. Fat diet statistically influences the decrease of
kidney mass in comparison to th
e other diets. The application
of the tested vanadium compound results also in the statistical
decrease of the fatty liver caused by fructose and fat diet.
keywords in English:
vanadium, high-fructose diet, bodymassgrowth, high-fatdiet, rat
departmental parameterization:
15
affiliation:
Wydział Farmaceutyczny : Zakład Chemii Bioorganicznej, Wydział Chemii : Zakład Chemii Nieorganicznej, Wydział Farmaceutyczny : Zakład Bromatologii