In our examinations, sixteen psychotropic drugs from the phenothiazines and tricyclic antidepressants group were studied. For the purpose o f screening analysis, the separation conditions of the drugs were studied using capillary electrophoresis in a non-aqueous medium. The influence of both background electrolyte composition and the kind o f medium used for dissolution o f the drugs on the separation efficiency was examined. Noxiptyline was selected as the internal standard. In optimal separation conditions, the identification parameter - relative migration time (RMT) - and repeatability of the identification parameter for each drug tested were determined.