Zjawisko Tamm-Horsfalla u noworodków

Bibliogr. s. 57

Background: Tamm-Horsfall phenomenon is a transient hyperechogenicity of the renal pyramids during the first few days of life. The purpose of this study was to determine whether there is a correlation between the Tamm-Horsfall phenomenon and the pathology of pregnancy, the kind of delivery, or selected biochemical parameters of urine. Material/Methods: The study involved 153 neonates, divided into two groups based on pregnancy age. Group I consisted of 118 full term neonates born in the 37th - 42nd week of pregnancy, while Group II included 35 premature neonates born before the 37th week of pregnancy. Ultrasonograms of the kidneys were performed on the 1st and 3rd day of life, as well as examinations of urine protein, creatinine, uric acid and urea concentration. The Examinations were repeated in the 2nd month of life after making a diagnosis of Tamm-Hosfall phenomenon. Results: Tamm-Horsfall phenomenon was diagnosed in 32 eutrophic children (22.7% of the group). Among the term neonates, diagnoses of Tamm-Horsfall phenomenon were made in 24.6% of the children (29/118), as opposed to 8.6% (3/35) in the preterm group in. Pregnancy was terminated by caesarean section in 22 cases (68.7 % of all 32). 10 children (31.3 % of all 32) were born spontaneously (p=0.01). Significantly higher urine protein and creatinine concentrations were noted in this group only on the 3rd day of life. Children with Tamm-Horsfall phenomenon had greater body mass at birth (p=0.01) than the others. Repeated examinations of 23 children diagnosed with Tamm-Horsfall phenomenon performed in the 2nd month of life showed that this phenomenon had disappeared. Conclusions: Tamm-Horsfall phenomenon is observed more often in children delivered by caesarean section. Children diagnosed with Tamm-Horsfall phenomenon have higher urine levels of protein and creatinine on the 3rd day of life. Tamm-Horsfall phenomenon is observed more often in term, eutrophic children.