Bibliogr. s. 13-14

Background: Transient monocular blindness (TMB) may appear as a consequence of vasospasm called the primary vasospastic syndrome. Because of pathogenesis of this disorder it is an essential diagnostic procedure in evaluation of hemodynamic disturbances in eyeball circulation system in group of TMB patients. The aim of this study was to investigate the changes in eyeball circulation in patients with TMB, using colour Doppler ultrasound imaging method (CDI). Material/Methods: 89 patients (59 women and 30 men) aged 34 to 56 (avg. 49.53, sd 3.15) with symptoms of transient blindness were examined using Acuson 128XP apparatus and sector probe frequency of 7.5 MHz. In ophthalmic artery (OA), central retinal artery (CRA) and short posterior temporal ciliary artery (SPTCA), the following parameters of blood flow were determined: peak systolic velocity (PSV, m/s), peak end - diastolic velocity (EDV, m/s), vascular pulsation index (PI) and resistance index (RI). The determined blood flow parameters were compared with the same blood flow indicators in the group of healthy individuals, matched for sex and age with the study group. T-Student test was applied in the statistical analysis of the differences between studied ocular blood flow parameters. In case of lack of normal variance, non - parametric U-Mann-Whitney test was used. Results: Statistical diminishing of average values of PSV (p =0.0001) in CRA and SPTCA; RI (p = 0.0001 in CRA and p = 0.0003 in SPTCA) and PI (in OA p = 0.0005, in CRA p = 0.0001, in SPTCA p = 0.0004) of examined eyes in comparison to healthy subjects was revealed. Peak-diastolic and mean velocities did not indicate statistically relevant difference in the control group. Conclusions: The statistically significant decrease of peak systolic parameters of blood flow velocity, pulsation and resistance indices in eyeball arteries were observed in patients with transient monocular blindness. Color Doppler ultrasonography was an effective and helpful method in assessing blood flow changes of eyeball microcirculation in transient monocular blindness.