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Background: Callosal anomalies account for approximately 2% of all CNS congenital malformations. Dysgenesis of the corpus callosum (complete or partial agenesis) can be an isolated CNS malformation or coexist with other pathologies. Case report: In all four cases corpus callosum dysgenesis was revealed by MRI (1.5T). The presented cases show examples of wide spectrum of all callosal anomalies - complete agenesis in case 1 and different sort of partial agenesis in cases 2, 3 and 4. In all the presented cases the callosal defect was found incidentally. Conclusions: Diagnostics of the corpus callosum malformations is based on ultrasound scans (pre- and postnatal), CT and most of all, the MR. Except for major callosal defects described in our report, MRI quite often reveals tiny anomalies of callosal shape. Corpus callosum defects can not only be congenital, but also caused by acquired disorders (traumatic, vascular, inflammatory and neoplastic).