Bibliogr. s. 75

Magnetic Resonance Spectroscopy (MRS) has become one of the most important imaging techniques of CNS recently thanks to the significant information concerning chemical compounds, which are produced in the metabolic processes in normal and pathological tissue. The techniques used most often in clinical practice are proton spectroscopy (1H MRS) and phosphor spectroscopy (31P MRS) as those elements play the crucial role in metabolic turn over [1-4]. The first gives information about various metabolic disorders (acethylaspartate acid - nervous cells marker, creatinin - related to metabolic changes, choline -element of cell membranes, lactates - markers of anaerobic metabolism). The second enables evaluation of energetic condition of the cells (phosphate compounds, mono- and biphosphate, phosphocreatinin, adenosine triphosphate ATP). Last years show tendency to quantitative method in spectroscopy. One of the solution seems to be LCModel, considered in this paper. Authors describe the basic techniques that are used in in vivo H MRS, P-MRS, C-MRS and possible applications of fMRSI technique as well as hyperpolarized C13.