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The value of perfusion CT in evaluating locoregional staging in post-radical prostatectomy patients with elevated serum PSA level
prostate
carcinoma
angiogenesis
prostate cancer
perfusion
Bibliogr. s. 17
Background: The aim of the study was to evaluate the efficiency of perfusion CT (p-CT) in assessing cancer foci in the prostate gland in patients with elevated PSA level who had radical prostatectomy after the p-CT exam. Material/Methods: Prostate p-CT was performed at the Oncology Institute, Cracow, in 2006 in 24 patients aged 49-72 years. The examination was followed by core needle biopsy of the prostate (6-12 cores). PSA levels in the blood ranged from 5.15 to 33.1 ng/ml. The Gleason score estimated after radical prostatectomy ranged from 5 to 8. The parameters BF, BV, PS, and MTT for both prostate lobes at three levels (base, mid-gland, and apex) were measured. Relationships between the presence of pathological foci found in p-CT, serum PSA level, and histopathological findings in the removed prostate gland were analyzed. Results/Conclusions: On the basis of the analyzed material, positive correlation was found between serum PSA level and Gleason score in the post-radical prostatectomy patients. Positive correlation was also found between serum PSA and the presence of pathological lesions detected in p-CT. The higher the level of serum PSA, the higher the probability of detecting a pathological lesion within the prostate gland. No significant correlation between histopathological and p-CT outcome concordance and serum PSA level was noted. However, no correlation between Gleason score and p-CT examination results was found, which suggests that there is no relationship between Gleason score and presence of pathological foci detected in p-CT examination.
dc.abstract.en | Background: The aim of the study was to evaluate the efficiency of perfusion CT (p-CT) in assessing cancer foci in the prostate gland in patients with elevated PSA level who had radical prostatectomy after the p-CT exam. Material/Methods: Prostate p-CT was performed at the Oncology Institute, Cracow, in 2006 in 24 patients aged 49-72 years. The examination was followed by core needle biopsy of the prostate (6-12 cores). PSA levels in the blood ranged from 5.15 to 33.1 ng/ml. The Gleason score estimated after radical prostatectomy ranged from 5 to 8. The parameters BF, BV, PS, and MTT for both prostate lobes at three levels (base, mid-gland, and apex) were measured. Relationships between the presence of pathological foci found in p-CT, serum PSA level, and histopathological findings in the removed prostate gland were analyzed. Results/Conclusions: On the basis of the analyzed material, positive correlation was found between serum PSA level and Gleason score in the post-radical prostatectomy patients. Positive correlation was also found between serum PSA and the presence of pathological lesions detected in p-CT. The higher the level of serum PSA, the higher the probability of detecting a pathological lesion within the prostate gland. No significant correlation between histopathological and p-CT outcome concordance and serum PSA level was noted. However, no correlation between Gleason score and p-CT examination results was found, which suggests that there is no relationship between Gleason score and presence of pathological foci detected in p-CT examination. | pl |
dc.contributor.author | Łuczyńska, Elżbieta | pl |
dc.contributor.author | Anioł, Joanna | pl |
dc.contributor.author | Stelmach, Andrzej | pl |
dc.contributor.author | Jaszczyński, Janusz | pl |
dc.date.accession | 2019-05-16 | pl |
dc.date.accessioned | 2019-05-16T12:03:46Z | |
dc.date.available | 2019-05-16T12:03:46Z | |
dc.date.issued | 2008 | pl |
dc.date.openaccess | 0 | |
dc.description.accesstime | w momencie opublikowania | |
dc.description.additional | Bibliogr. s. 17 | pl |
dc.description.number | 2 | pl |
dc.description.physical | 13-17 | pl |
dc.description.version | ostateczna wersja wydawcy | |
dc.description.volume | 73 | pl |
dc.identifier.articleid | 857100 | pl |
dc.identifier.eissn | 1899-0967 | pl |
dc.identifier.issn | 1733-134X | pl |
dc.identifier.project | ROD UJ / OP | pl |
dc.identifier.uri | https://ruj.uj.edu.pl/xmlui/handle/item/74942 | |
dc.identifier.weblink | http://archiwum.inforadiologia.pl/download/index/idArt/857100.html | pl |
dc.language | eng | pl |
dc.language.container | eng | pl |
dc.rights | Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa | * |
dc.rights.licence | CC-BY-NC-ND | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl | * |
dc.share.type | otwarte czasopismo | |
dc.subject.en | prostate | pl |
dc.subject.en | carcinoma | pl |
dc.subject.en | angiogenesis | pl |
dc.subject.en | prostate cancer | pl |
dc.subject.en | perfusion | pl |
dc.subtype | Article | pl |
dc.title | The value of perfusion CT in evaluating locoregional staging in post-radical prostatectomy patients with elevated serum PSA level | pl |
dc.title.journal | Polish Journal of Radiology | pl |
dc.type | JournalArticle | pl |
dspace.entity.type | Publication |
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