Bibliogr. s. 15

Background: The aim of this study was to compare prostate 1H-MRS spectrum obtained with a surface coil at 3T and at 1,5T system with an endorectal coil. Chemical shift and possibility of metabolite characterization present in the prostate gland were taken into consideration. Material/Methods: Our study comprised 15 randomly chosen patients (age 51-77 years, mean 66.2±7.7). 1HMRS examination was performed using an endorectal coil (Medrad) with 1,5T (Siemens Avanto) scanning unit. Our study additionally included 15 patients (age 52-77 years, mean 66.3±7.7) whose examination was performed with a 6-channel surface coil at 3T (Philips Avanto) system. Evaluated factors: 1. resolution - understood as the possibility to resolve Cho (3.2 ppm) and Cr (3 ppm) peaks; 2. character of Cit peak (2.6 ppm); 3. spermine detection (3.1 ppm). Results: Among spectrums obtained at 1,5T using an endorectal coil in 54/150 (36%) Cho (3.2 ppm) and Cr (3 ppm) peaks were clearly separated. In 94/150 (64%) Cho (3.2 ppm) and Cr (3 ppm) peaks were not resolved - visible as overlapping peaks. In all Cit (2.6 ppm) spectrums, the peak was visible as a singlet or as a nonsymmetrical shape singlet. The spermine peak (3.1 ppm) was not detected in any spectrum. In all 150/150 (100%) spectrums obtained at 3T using a 6-channel surface coil, Cho (3.2 ppm) and Cr (3ppm) peaks were clearly resolved, visible as separated peaks. In 137/150 (91%) Cit (2.6 ppm) resonance was visible as a triplet or as a triplet with a nonsymmetrical central peak. In 10/150 (6,6%) spectrums, a spermine peak (3.1 ppm) was detected. Conclusions: 1. Prostate examination using a surface coil at 3T allows to obtain a spectrum of the same or better quality in comparison with a spectrum obtained at 1,5T using an endorectal coil. 2. Cho and Cr peaks separation is statistically significantly more possible at 3T than at 1,5T; 3. Cit peak was always visible as a multiplet at 3T and never at 1,5T; 4. Spermine peak was detected in 10/150 spectrums (6.6%).