Repozytorium Uniwersytetu Jagiellońskiego

Neurosurgical treatment of drug-resistant epilepsy on the basis of a fusion of MRI and SPECT images : case report

Neurosurgical treatment of drug-resistant epilepsy ...

Metadane (Dublin Core)

dc.contributor.author Jurkiewicz, Elżbieta pl
dc.contributor.author Bekiesińska-Figatowska, Monika pl
dc.contributor.author Miśko, Jolanta pl
dc.contributor.author Kamińska, Anna pl
dc.contributor.author Kwiatkowski, Stanisław pl
dc.contributor.author Terczyńska, Iwona pl
dc.date.accessioned 2018-10-11T11:26:58Z
dc.date.available 2018-10-11T11:26:58Z
dc.date.issued 2010 pl
dc.identifier.issn 1733-134X pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/57895
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/pl/legalcode *
dc.title Neurosurgical treatment of drug-resistant epilepsy on the basis of a fusion of MRI and SPECT images : case report pl
dc.title.alternative Neurochirurgiczne leczenie lekoopornej padaczki na podstawie fuzji obrazów MR i SPECT : opis przypadku pl
dc.type JournalArticle pl
dc.description.physical 51-54 pl
dc.description.additional Bibliogr. s. 54 pl
dc.identifier.weblink http://archiwum.polradiol.com/download/index/idArt/881149.html pl
dc.abstract.en Background: Epilepsy concerns at least 0.5% of population and in most of the cases (approx. 70%) can be treated pharmacologically, which helps to prevent seizures. In all other patients, such a treatment does not produce the desired results. Their condition may require neurosurgical management. The aim of this work was to fuse anatomical MRI images and functional SPECT images in patients with drugresistant epilepsy, without structural changes on MRI or with changes so severe that it would be impossible to establish which ones are responsible for seizures. The authors presented a case of a child subjected to a neurosurgical procedure carried out on the basis of the fused MRI and SPECT images. Case Report: A seven-year-old boy with an extensive defect of the right hemisphere (cortical dysplasia with multiple balloon-like cells) operated on three times due to a history of treatment-resistant seizures present since the age of one. A subsequent MRI examination was performed with magnetic field intensity of 1.5 T, within a routine epilepsy protocol applying volumetric thin-slice T1-weighted images. Next, in the interictal period, a SPECT examination was performed with the use of the 99mTc-labelled ethyl cysteinate dimer (99mTcECD). For fusion and postprocessing, the following software was used: PMOD (Biomedical Image Quantification PMOD Technologies) with PFUS (Flexible Image Matching and Fusion Tool) and a program for a quantitative analysis of counts in the region of interest, so called VOI Constructor (Volume of Interest Constructor). On the basis of the fusion of images, the boy was subjected to the next operation procedure. The remaining fragments of the right frontal and parietal lobe adjacent to the occipital lobe were removed. Seizure remission was obtained and it was already 31 months long when we were writing this article. Conclusions: Owing to this multi-stage procedure, it was possible to avoid a total anatomical and functional hemispherectomy. This allowed for a resection limited to regions indicated by integrated imaging. Removal of cortical areas including lesions was advantageous in this presented case, as it allowed for saving active regions of the brain. pl
dc.subject.en drug-resistant epilepsy pl
dc.subject.en brain pl
dc.subject.en magnetic resonance imaging (MRI) pl
dc.subject.en single photon emission computed tomography (SPECT) pl
dc.subject.en fusion of the images pl
dc.description.volume 75 pl
dc.description.number 3 pl
dc.identifier.eissn 1899-0967 pl
dc.title.journal Polish Journal of Radiology pl
dc.language.container eng pl
dc.date.accession 2018-10-11 pl
dc.subtype Article pl
dc.identifier.articleid 881149 pl
dc.rights.original CC-BY-NC-ND; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa Poza zaznaczonymi wyjątkami, licencja tej pozycji opisana jest jako Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa