Diagnostic value of gadolinium-enhanced MR imaging of active sacroiliitis in seronegative spondyloarthropathy

2010
journal article
article
dc.abstract.enBackground: Seronegative spondyloarthropathy (SpA) is a group of diseases including: ankylosing spondylitis, psoriatic spondyloarthrithis, reactive arthritis, spondyloarthrithis associated with inflammatory bowel disease, and undifferentiated spondyloarthritis. One of the diagnostic criteria of SpA is the presence of sacroiliitis. Periarticular bone marrow oedema (histologically corresponding to osteitis) is a primary symptom of the active stage of inflammation, which can be identified by MR using T2-weighted images. Its presence is essential for the therapeutic decision. The aims of this study were: 1. to compare the diagnostic value of T2-weighted images with T1 gadolinium-enhanced fat saturation (FS) images. 2. to establish if T1 gadolinium-enhanced images increase the diagnostic value of the MRI examination. Material/Methods: With the use of a 1.5T MRI scanner, 35 patients aged 19-67 years were examined. They were classified as having SpA or suspicious of SpA. The following findings were assessed: bone marrow oedema, synovitis, capsulitis/enthesistis. They were evaluated and compared on T2 and T1 gadolinium-enhanced FS images. Results: Active sacroiliitis was identified in 21 patients, chronic in 1 patient. Two patients had signs of synovitis without any features of bone marrow oedema. One patient had fracture of the sacral bone. Ten patients had no signs of sacroiliitis. There was no significant difference in the diagnostic value between FSE T2 images and T1 gadolinium-enhanced images with FS in the evaluation of bone marrow oedema and capsulitis/enthesitis. However, T1 gadolinium-enhanced images were more sensitive than FSE T2 images in visualising synovitis. Conclusions: MRI is a very sensitive method to identify active sacroiliitis in SpA. MRI without contrast administration is sufficient to identify bone marrow oedema as a crucial finding in active sacroiliitis. The gadolinium-enhanced images make the diagnosis easier, especially in patients with minimal bone marrow oedema because they reveal or better depict synovitis, while they do not improve visualisation of capsulitis/enthesitis.pl
dc.contributor.authorMaksymowicz, Hannapl
dc.contributor.authorKowalewski, Krzysztofpl
dc.contributor.authorLubkowska, Katarzynapl
dc.contributor.authorŻołud, Wojciechpl
dc.contributor.authorSąsiadek, Marekpl
dc.date.accession2018-10-10pl
dc.date.accessioned2018-10-10T15:12:34Z
dc.date.available2018-10-10T15:12:34Z
dc.date.issued2010pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. 64-65pl
dc.description.number2pl
dc.description.physical58-65pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume75pl
dc.identifier.articleid878518pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/57821
dc.identifier.weblinkhttp://archiwum.polradiol.com/download/index/idArt/878518.htmlpl
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enseronegative spondyloarthropathiespl
dc.subject.ensacroiliitispl
dc.subject.enmagnetic resonancepl
dc.subtypeArticlepl
dc.titleDiagnostic value of gadolinium-enhanced MR imaging of active sacroiliitis in seronegative spondyloarthropathypl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Background: Seronegative spondyloarthropathy (SpA) is a group of diseases including: ankylosing spondylitis, psoriatic spondyloarthrithis, reactive arthritis, spondyloarthrithis associated with inflammatory bowel disease, and undifferentiated spondyloarthritis. One of the diagnostic criteria of SpA is the presence of sacroiliitis. Periarticular bone marrow oedema (histologically corresponding to osteitis) is a primary symptom of the active stage of inflammation, which can be identified by MR using T2-weighted images. Its presence is essential for the therapeutic decision. The aims of this study were: 1. to compare the diagnostic value of T2-weighted images with T1 gadolinium-enhanced fat saturation (FS) images. 2. to establish if T1 gadolinium-enhanced images increase the diagnostic value of the MRI examination. Material/Methods: With the use of a 1.5T MRI scanner, 35 patients aged 19-67 years were examined. They were classified as having SpA or suspicious of SpA. The following findings were assessed: bone marrow oedema, synovitis, capsulitis/enthesistis. They were evaluated and compared on T2 and T1 gadolinium-enhanced FS images. Results: Active sacroiliitis was identified in 21 patients, chronic in 1 patient. Two patients had signs of synovitis without any features of bone marrow oedema. One patient had fracture of the sacral bone. Ten patients had no signs of sacroiliitis. There was no significant difference in the diagnostic value between FSE T2 images and T1 gadolinium-enhanced images with FS in the evaluation of bone marrow oedema and capsulitis/enthesitis. However, T1 gadolinium-enhanced images were more sensitive than FSE T2 images in visualising synovitis. Conclusions: MRI is a very sensitive method to identify active sacroiliitis in SpA. MRI without contrast administration is sufficient to identify bone marrow oedema as a crucial finding in active sacroiliitis. The gadolinium-enhanced images make the diagnosis easier, especially in patients with minimal bone marrow oedema because they reveal or better depict synovitis, while they do not improve visualisation of capsulitis/enthesitis.
dc.contributor.authorpl
Maksymowicz, Hanna
dc.contributor.authorpl
Kowalewski, Krzysztof
dc.contributor.authorpl
Lubkowska, Katarzyna
dc.contributor.authorpl
Żołud, Wojciech
dc.contributor.authorpl
Sąsiadek, Marek
dc.date.accessionpl
2018-10-10
dc.date.accessioned
2018-10-10T15:12:34Z
dc.date.available
2018-10-10T15:12:34Z
dc.date.issuedpl
2010
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. 64-65
dc.description.numberpl
2
dc.description.physicalpl
58-65
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
75
dc.identifier.articleidpl
878518
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/57821
dc.identifier.weblinkpl
http://archiwum.polradiol.com/download/index/idArt/878518.html
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
seronegative spondyloarthropathies
dc.subject.enpl
sacroiliitis
dc.subject.enpl
magnetic resonance
dc.subtypepl
Article
dc.titlepl
Diagnostic value of gadolinium-enhanced MR imaging of active sacroiliitis in seronegative spondyloarthropathy
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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