A Time Domain Reflectometer implemented in a single cost-effective Field Programmable Gate Array device is shown to achieve a precision around 100ps. The Time to Digital Converter section of the device is based on a tapped delay line followed by an encoder and shows both Differential and Integral Non-Linearity below one least significant bit. The same Field Programmable Gate Array houses an 8051 8-bits microprocessor, for the control of the pulse signals generation, the acquisition and the first treatment of raw data. Principles of operation, architecture, performance and preliminary trials on the prototype are presented in this paper. As an example of possible application, the proposed circuit has been usefully used to perform the quality control of the micro-strip anodic planes of the Gas Electron Multiplier Inner Tracker of the KLOE-2 experiment.