Tracer diffusion inside fibrinogen layers

Bibliographic description

punktacja MNiSW [2014 A]: 35

title:	Tracer diffusion inside fibrinogen layers
author:	Cieśla Michał , Gudowska-Nowak Ewa , Sagués Francesc, Sokolov Igor M.
journal title:	The Journal of Chemical Physics
volume:	140
issue:	4
date of publication :	2014
article ID:	044706
ISSN:	0021-9606
eISSN:	1089-7690 1520-9032
DOI:	10.1063/1.4862170
language:	English
journal language:	English
abstract in English:	We investigate the obstructed motion of tracer (test) particles in crowded environments by carrying simulations of two-dimensional Gaussian random walk in model fibrinogen monolayers of different orientational ordering. The fibrinogen molecules are significantly anisotropic and therefore they can form structures where orientational ordering, similar to the one observed in nematic liquid crystals, appears. The work focuses on the dependence between level of the orientational order (degree of environmental crowding) of fibrinogen molecules inside a layer and non-Fickian character of the diffusion process of spherical tracer particles moving within the domain. It is shown that in general particles motion is subdiffusive and strongly anisotropic, and its characteristic features significantly change with the orientational order parameter, concentration of fibrinogens, and radius of a diffusing probe.
affiliation:	Wydział Fizyki, Astronomii i Informatyki Stosowanej : Instytut Fizyki im. Mariana Smoluchowskiego
type:	journal article
subtype:	academic paper

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