Estimating influence of positron range in proton therapy beam monitoring with PET

2023
journal article
article
cris.lastimport.wos2024-04-10T02:13:03Z
dc.abstract.enApplication of PET scanners to proton beam therapy monitoring is a promising solution to obtain the range of the beam and hence the positions of a Bragg peak - maximum dose deposition point. Proton beam induces in the tissue nuclear reactions, leading to production of isotopes that emit β+ radiation. This enables the imaging of the density distribution of β+ isotopes produced in the body, allowing for the reconstruction of the proton beam range. Moreover, PET detectors may open the possibility of in-beam monitoring, which would give an opportunity of verifying the range during the irradiation. PET detectors may also allow positronium imaging, which would be the indicator of the tissue conditions. However, the image of annihilation points does not represent the range of the proton beam. There are several factors influencing the translation from annihilation points to obtain the Bragg peak position. One of them is the kinetic energy of the positron. This energy corresponds to some range of the positron within the tissue. In this manuscript, we estimate the positron energy and its range and discuss its influence on the proton therapy monitoring.pl
dc.affiliationWydział Fizyki, Astronomii i Informatyki Stosowanej : Instytut Fizyki im. Mariana Smoluchowskiegopl
dc.affiliationSzkoła Doktorska Nauk Ścisłych i Przyrodniczychpl
dc.contributor.authorMryka, Wiktor - 385379 pl
dc.contributor.authorDas, Manish - 478556 pl
dc.contributor.authorBeyene, Ermias Yitayew - 473796 pl
dc.contributor.authorMoskal, Paweł - 100401 pl
dc.contributor.authorStępień, Ewa - 161583 pl
dc.contributor.institutionJ-PET collaborationpl
dc.date.accessioned2024-01-30T11:20:21Z
dc.date.available2024-01-30T11:20:21Z
dc.date.issued2023pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.number1pl
dc.description.physical96-100pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume19pl
dc.identifier.doi10.5604/01.3001.0054.1939pl
dc.identifier.eissn1896-530Xpl
dc.identifier.issn1895-9091pl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/326452
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa*
dc.rights.licenceCC-BY
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enproton therapypl
dc.subject.enpositron rangepl
dc.subject.enpositron emission tomography (PET)pl
dc.subject.enbeta spectrapl
dc.subject.enproton beam monitoringpl
dc.subtypeArticlepl
dc.titleEstimating influence of positron range in proton therapy beam monitoring with PETpl
dc.title.journalBio-Algorithms and Med-Systemspl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-10T02:13:03Z
dc.abstract.enpl
Application of PET scanners to proton beam therapy monitoring is a promising solution to obtain the range of the beam and hence the positions of a Bragg peak - maximum dose deposition point. Proton beam induces in the tissue nuclear reactions, leading to production of isotopes that emit β+ radiation. This enables the imaging of the density distribution of β+ isotopes produced in the body, allowing for the reconstruction of the proton beam range. Moreover, PET detectors may open the possibility of in-beam monitoring, which would give an opportunity of verifying the range during the irradiation. PET detectors may also allow positronium imaging, which would be the indicator of the tissue conditions. However, the image of annihilation points does not represent the range of the proton beam. There are several factors influencing the translation from annihilation points to obtain the Bragg peak position. One of them is the kinetic energy of the positron. This energy corresponds to some range of the positron within the tissue. In this manuscript, we estimate the positron energy and its range and discuss its influence on the proton therapy monitoring.
dc.affiliationpl
Wydział Fizyki, Astronomii i Informatyki Stosowanej : Instytut Fizyki im. Mariana Smoluchowskiego
dc.affiliationpl
Szkoła Doktorska Nauk Ścisłych i Przyrodniczych
dc.contributor.authorpl
Mryka, Wiktor - 385379
dc.contributor.authorpl
Das, Manish - 478556
dc.contributor.authorpl
Beyene, Ermias Yitayew - 473796
dc.contributor.authorpl
Moskal, Paweł - 100401
dc.contributor.authorpl
Stępień, Ewa - 161583
dc.contributor.institutionpl
J-PET collaboration
dc.date.accessioned
2024-01-30T11:20:21Z
dc.date.available
2024-01-30T11:20:21Z
dc.date.issuedpl
2023
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.numberpl
1
dc.description.physicalpl
96-100
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
19
dc.identifier.doipl
10.5604/01.3001.0054.1939
dc.identifier.eissnpl
1896-530X
dc.identifier.issnpl
1895-9091
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/326452
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa
dc.rights.licence
CC-BY
dc.rights.uri*
http://creativecommons.org/licenses/by/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
proton therapy
dc.subject.enpl
positron range
dc.subject.enpl
positron emission tomography (PET)
dc.subject.enpl
beta spectra
dc.subject.enpl
proton beam monitoring
dc.subtypepl
Article
dc.titlepl
Estimating influence of positron range in proton therapy beam monitoring with PET
dc.title.journalpl
Bio-Algorithms and Med-Systems
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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