Validation of the usefulness of dose calculation algorithms in radiotherapy planning system

2016
journal article
article
cris.lastimport.wos2024-04-09T19:31:43Z
dc.abstract.enOne of the main goals of radiotherapy is to achieve tumor control and minimize probability of normal-tissue complications. For this reason radiation oncology requires high accuracy, which implies no more than 2-3% uncertainty levels in the treatment planning calculations. That is challenging, when heterogeneous tissues such as lungs and bones are involved. To verify the accuracy of the dose calculation algorithms numerous approaches might be performed. The most common are point dose, one-dimensional profile and two-dimensional isodose line comparison with experimental measurements. In presented study, results of transport modeling and the deposited spatial distribution of the dose, obtained by anisotropic analytical algorithm and pencil beam convolution algorithm, were compared to measurements recorded during the experiment. To achieve meaningful conclusions, three parameters: dose difference, distance to agreement and gamma parameter (γ) were taken into consideration and examined. The irradiation was performed using CIRS anthropomorphic phantom. For dose detection gafchromic EBT films were used and scanned after exposure using Epson Scanner. Measured and planned dose distributions were analyzed via FilmQA software. Preliminary results showed that the anisotropic analytical algorithm, with its complex accounting of heterogeneities, provides more accurate dose calculation within an area of a high density gradient, than pencil beam convolution does. The level of the data accuracy derived from the experiment was: dose difference (5%) - 83.4% and 68% pixels passing, distance to agreement (3 mm) - 99.0% and 96.7%, gamma parameter (for dose difference (3%), distance to agreement (3 mm)) - 90% and 75.5%, respectively, for anisotropic analytical algorithm and pencil beam convolution algorithms. The comparison between studied parameters dose difference, distance to agreement and γ for both algorithms implicated anisotropic analytical algorithm as an appropriate approach in radiotherapy treatment planning.pl
dc.affiliationWydział Fizyki, Astronomii i Informatyki Stosowanej : Instytut Fizyki im. Mariana Smoluchowskiegopl
dc.contributor.authorKiełtyka, Bartosz - 164788 pl
dc.contributor.authorRawojć, Kamila - 212300 pl
dc.contributor.authorKisielewicz, K.pl
dc.contributor.authorMarkiewicz, I.pl
dc.date.accessioned2016-06-28T13:28:49Z
dc.date.available2016-06-28T13:28:49Z
dc.date.issued2016pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.number2pl
dc.description.physical219-221pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume129pl
dc.identifier.doi10.12693/APhysPolA.129.219pl
dc.identifier.eissn1898-794Xpl
dc.identifier.issn0587-4246pl
dc.identifier.projectROD UJ / Ppl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/28403
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceInna otwarta licencja
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subtypeArticlepl
dc.titleValidation of the usefulness of dose calculation algorithms in radiotherapy planning systempl
dc.title.journalActa Physica Polonica. Apl
dc.title.volumeProceedings of the 50th Zakopane School of Physics International Symposium Breaking Frontiers: Submicron Structures in Physics and Biology, Zakopane, Poland, May 18-23, 2015pl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-09T19:31:43Z
dc.abstract.enpl
One of the main goals of radiotherapy is to achieve tumor control and minimize probability of normal-tissue complications. For this reason radiation oncology requires high accuracy, which implies no more than 2-3% uncertainty levels in the treatment planning calculations. That is challenging, when heterogeneous tissues such as lungs and bones are involved. To verify the accuracy of the dose calculation algorithms numerous approaches might be performed. The most common are point dose, one-dimensional profile and two-dimensional isodose line comparison with experimental measurements. In presented study, results of transport modeling and the deposited spatial distribution of the dose, obtained by anisotropic analytical algorithm and pencil beam convolution algorithm, were compared to measurements recorded during the experiment. To achieve meaningful conclusions, three parameters: dose difference, distance to agreement and gamma parameter (γ) were taken into consideration and examined. The irradiation was performed using CIRS anthropomorphic phantom. For dose detection gafchromic EBT films were used and scanned after exposure using Epson Scanner. Measured and planned dose distributions were analyzed via FilmQA software. Preliminary results showed that the anisotropic analytical algorithm, with its complex accounting of heterogeneities, provides more accurate dose calculation within an area of a high density gradient, than pencil beam convolution does. The level of the data accuracy derived from the experiment was: dose difference (5%) - 83.4% and 68% pixels passing, distance to agreement (3 mm) - 99.0% and 96.7%, gamma parameter (for dose difference (3%), distance to agreement (3 mm)) - 90% and 75.5%, respectively, for anisotropic analytical algorithm and pencil beam convolution algorithms. The comparison between studied parameters dose difference, distance to agreement and γ for both algorithms implicated anisotropic analytical algorithm as an appropriate approach in radiotherapy treatment planning.
dc.affiliationpl
Wydział Fizyki, Astronomii i Informatyki Stosowanej : Instytut Fizyki im. Mariana Smoluchowskiego
dc.contributor.authorpl
Kiełtyka, Bartosz - 164788
dc.contributor.authorpl
Rawojć, Kamila - 212300
dc.contributor.authorpl
Kisielewicz, K.
dc.contributor.authorpl
Markiewicz, I.
dc.date.accessioned
2016-06-28T13:28:49Z
dc.date.available
2016-06-28T13:28:49Z
dc.date.issuedpl
2016
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.numberpl
2
dc.description.physicalpl
219-221
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
129
dc.identifier.doipl
10.12693/APhysPolA.129.219
dc.identifier.eissnpl
1898-794X
dc.identifier.issnpl
0587-4246
dc.identifier.projectpl
ROD UJ / P
dc.identifier.uri
http://ruj.uj.edu.pl/xmlui/handle/item/28403
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
Inna otwarta licencja
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subtypepl
Article
dc.titlepl
Validation of the usefulness of dose calculation algorithms in radiotherapy planning system
dc.title.journalpl
Acta Physica Polonica. A
dc.title.volumepl
Proceedings of the 50th Zakopane School of Physics International Symposium Breaking Frontiers: Submicron Structures in Physics and Biology, Zakopane, Poland, May 18-23, 2015
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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