Simple view
Full metadata view
Authors
Statistics
Low-cost, programmable infusion pump with bolus mode for in-vivo imaging
syringe pump
electron resonance imaging (ERI)
simulation of physiological processes
Arduino
3D printing
Syringe pumps are routinely used in biomedical imaging laboratories for delivering contrast agents and either infusing or injecting a precise amount of liquids. Commercial syringe pumps that are developed by specialized companies are expensive and only have standard functions, which often do not meet the requirements of individual experiments. In this paper, we demonstrate an open-source single syringe pump with the possibility of adapting to the needs of a researcher. The device that was designed, is controlled by an Arduino Leonardo, along with the stepper motor driver. For sending commands and receiving the current plunger position, a C# software was developed with serial communication via USB. Additionally, the 3D models were made in a universal way, which allows for the use of any syringe size. An example of the application of the syringe pump for biomedical applications was demonstrated using electron resonance imaging (ERI). The single syringe pump tests were demonstrated by simulating the filling of a particular volume inside the resonator. This example reflects the clearance process after an intravascular (I.V) drug administration in the murine model. The experiments were performed on an ERI TM 600 tomograph. The results confirmed that the designed syringe pump allowed for controlling the infusion speed and injected volume. Moreover, we present a user-friendly and opensource graphical interface that is a low-cost alternative for commercial devices.
cris.lastimport.wos | 2024-04-09T19:22:33Z | |
dc.abstract.en | Syringe pumps are routinely used in biomedical imaging laboratories for delivering contrast agents and either infusing or injecting a precise amount of liquids. Commercial syringe pumps that are developed by specialized companies are expensive and only have standard functions, which often do not meet the requirements of individual experiments. In this paper, we demonstrate an open-source single syringe pump with the possibility of adapting to the needs of a researcher. The device that was designed, is controlled by an Arduino Leonardo, along with the stepper motor driver. For sending commands and receiving the current plunger position, a C# software was developed with serial communication via USB. Additionally, the 3D models were made in a universal way, which allows for the use of any syringe size. An example of the application of the syringe pump for biomedical applications was demonstrated using electron resonance imaging (ERI). The single syringe pump tests were demonstrated by simulating the filling of a particular volume inside the resonator. This example reflects the clearance process after an intravascular (I.V) drug administration in the murine model. The experiments were performed on an ERI TM 600 tomograph. The results confirmed that the designed syringe pump allowed for controlling the infusion speed and injected volume. Moreover, we present a user-friendly and opensource graphical interface that is a low-cost alternative for commercial devices. | pl |
dc.affiliation | Wydział Biochemii, Biofizyki i Biotechnologii | pl |
dc.contributor.author | Kujawa, Maciej | pl |
dc.contributor.author | Motała, Szymon | pl |
dc.contributor.author | Gonet, Michał - 164923 | pl |
dc.contributor.author | Pietrzyk, Rafał | pl |
dc.contributor.author | Czechowski, Tomasz | pl |
dc.contributor.author | Baranowski, Mikołaj | pl |
dc.date.accessioned | 2021-10-22T11:44:59Z | |
dc.date.available | 2021-10-22T11:44:59Z | |
dc.date.issued | 2021 | pl |
dc.date.openaccess | 0 | |
dc.description.accesstime | w momencie opublikowania | |
dc.description.version | ostateczna wersja wydawcy | |
dc.description.volume | 9 | pl |
dc.identifier.articleid | e00194 | pl |
dc.identifier.doi | 10.1016/j.ohx.2021.e00194 | pl |
dc.identifier.eissn | 2468-0672 | pl |
dc.identifier.project | ROD UJ / O | pl |
dc.identifier.uri | https://ruj.uj.edu.pl/xmlui/handle/item/281375 | |
dc.language | eng | pl |
dc.language.container | eng | pl |
dc.rights | Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa | * |
dc.rights.licence | CC-BY-NC-ND | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl | * |
dc.share.type | otwarte czasopismo | |
dc.subject.en | syringe pump | pl |
dc.subject.en | electron resonance imaging (ERI) | pl |
dc.subject.en | simulation of physiological processes | pl |
dc.subject.en | Arduino | pl |
dc.subject.en | 3D printing | pl |
dc.subtype | Article | pl |
dc.title | Low-cost, programmable infusion pump with bolus mode for in-vivo imaging | pl |
dc.title.journal | HardwareX | pl |
dc.type | JournalArticle | pl |
dspace.entity.type | Publication |
* The migration of download and view statistics prior to the date of April 8, 2024 is in progress.
Views
13
Views per month
Views per city
Downloads
Open Access