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The importance of diffusion apparent diffusion coefficient values in the evaluation of soft tissue sarcomas after treatment
MR imaging
diffusion-weighted magnetic resonance imaging
soft tissue tumours
recurrent sarcomas
posttreatment change
Bibliogr. s. e297
Purpose: In our study, we aimed to show the efficiency of diffusion-weighted images at different b-values and apparent diffusion coefficient (ADC) values in the differentiation of recurrent tumours from post-treatment tissue changes. Material and methods: The conventional and diffusion magnetic resonance images (MRIs) of 42 patients operated for soft tissue sarcomas between June 2012 and March 2015 followed up with MRIs that were evaluated by 2 radiologists retrospectively. Diffusion MRIs were acquired at 4 different b-values (50, 400, 800, 1000 s/mm2). The lesions were classified according to conventional MRI findings as post-treatment changes and recurrent tumours. Results: When the patient group with recurrent tumours was compared with the patient group with postoperative changes the ADC calculations were statistically significantly lower for the recurrent tumours at all b-levels (p < 0.001 for all b-levels). The sensitivity of b-50 values lower than 3.01 × 103 mm²/s in showing recurrent tumours was 100% and the specificity was 77.78%. The sensitivity of b-400 values lower than 2.1 × 103 mm²/s in showing recurrent tumours was 80% and the specificity was 96.3%. The sensitivity of b-800 values lower than 2.26 × 103 mm²/s in showing recurrent tumours was 100% and the specificity was 88.89%. The sensitivity of b-1000 values lower than 2 × 103 mm²/s in showing recurrent tumours was 93.3% and the specificity was 92.5%. Conclusions: The ADC values obtained from diffusion-weighted images have high sensitivity and specificity in differentiating recurring soft tissue sarcomas during monitoring after treatment from postoperative changes.
cris.lastimport.wos | 2024-04-09T20:08:15Z | |
dc.abstract.en | Purpose: In our study, we aimed to show the efficiency of diffusion-weighted images at different b-values and apparent diffusion coefficient (ADC) values in the differentiation of recurrent tumours from post-treatment tissue changes. Material and methods: The conventional and diffusion magnetic resonance images (MRIs) of 42 patients operated for soft tissue sarcomas between June 2012 and March 2015 followed up with MRIs that were evaluated by 2 radiologists retrospectively. Diffusion MRIs were acquired at 4 different b-values (50, 400, 800, 1000 s/mm2). The lesions were classified according to conventional MRI findings as post-treatment changes and recurrent tumours. Results: When the patient group with recurrent tumours was compared with the patient group with postoperative changes the ADC calculations were statistically significantly lower for the recurrent tumours at all b-levels (p < 0.001 for all b-levels). The sensitivity of b-50 values lower than 3.01 × 103 mm²/s in showing recurrent tumours was 100% and the specificity was 77.78%. The sensitivity of b-400 values lower than 2.1 × 103 mm²/s in showing recurrent tumours was 80% and the specificity was 96.3%. The sensitivity of b-800 values lower than 2.26 × 103 mm²/s in showing recurrent tumours was 100% and the specificity was 88.89%. The sensitivity of b-1000 values lower than 2 × 103 mm²/s in showing recurrent tumours was 93.3% and the specificity was 92.5%. Conclusions: The ADC values obtained from diffusion-weighted images have high sensitivity and specificity in differentiating recurring soft tissue sarcomas during monitoring after treatment from postoperative changes. | pl |
dc.contributor.author | Aktas, Elif | pl |
dc.contributor.author | Arikan, Sefik M. | pl |
dc.contributor.author | Ardıç, Fisun | pl |
dc.contributor.author | Savran, Burcu | pl |
dc.contributor.author | Arslan, Alaettin | pl |
dc.contributor.author | Toğral, Güray | pl |
dc.contributor.author | Karakaya, Jale | pl |
dc.contributor.author | Aribas, Bilgin K. | pl |
dc.date.accessioned | 2021-05-31T14:34:48Z | |
dc.date.available | 2021-05-31T14:34:48Z | |
dc.date.issued | 2021 | pl |
dc.date.openaccess | 0 | |
dc.description.accesstime | w momencie opublikowania | |
dc.description.additional | Bibliogr. s. e297 | pl |
dc.description.physical | e291-e297 | pl |
dc.description.version | ostateczna wersja wydawcy | |
dc.description.volume | 86 | pl |
dc.identifier.doi | 10.5114/pjr.2021.106413 | pl |
dc.identifier.eissn | 1899-0967 | pl |
dc.identifier.issn | 1733-134X | pl |
dc.identifier.uri | https://ruj.uj.edu.pl/xmlui/handle/item/271993 | |
dc.language | eng | pl |
dc.language.container | eng | pl |
dc.rights | Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa | * |
dc.rights.licence | CC-BY-NC-ND | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl | * |
dc.share.type | otwarte czasopismo | |
dc.subject.en | MR imaging | pl |
dc.subject.en | diffusion-weighted magnetic resonance imaging | pl |
dc.subject.en | soft tissue tumours | pl |
dc.subject.en | recurrent sarcomas | pl |
dc.subject.en | posttreatment change | pl |
dc.subtype | Article | pl |
dc.title | The importance of diffusion apparent diffusion coefficient values in the evaluation of soft tissue sarcomas after treatment | pl |
dc.title.journal | Polish Journal of Radiology | pl |
dc.type | JournalArticle | pl |
dspace.entity.type | Publication |
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