The memory-modifying potential of optogenetics and the need for neuroethics

2020
journal article
article
24
dc.abstract.enOptogenetics is an invasive neuromodulation technology involving the use of light to control the activity of individual neurons. Even though optogenetics is a relatively new neuromodulation tool whose various implications have not yet been scrutinized, it has already been approved for its first clinical trials in humans. As optogenetics is being intensively investigated in animal models with the aim of developing novel brain stimulation treatments for various neurological and psychiatric disorders, it appears crucial to consider both the opportunities and dangers such therapies may offer. In this review, we focus on the memory-modifying potential of optogenetics, investigating what it is capable of and how it differs from other memory modification technologies (MMTs). We then outline the safety challenges that need to be addressed before optogenetics can be used in humans. Finally, we re-examine crucial neuroethical concerns expressed in regard to other MMTs in the light of optogenetics and address those that appear to be unique to the memory-modifying potential of optogenetic technology.pl
dc.affiliationWydział Filozoficzny : Instytut Psychologiipl
dc.affiliationWydział Filozoficzny : Instytut Filozofiipl
dc.contributor.authorAdamczyk, Agnieszka - 231689 pl
dc.contributor.authorZawadzki, Przemysław - 221740 pl
dc.date.accessioned2020-12-06T21:50:08Z
dc.date.available2020-12-06T21:50:08Z
dc.date.issued2020pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. 221-225. Autorka podpisana na pub.: Agnieszka K. Adamczykpl
dc.description.number3pl
dc.description.physical207-225pl
dc.description.points70pl
dc.description.publication1pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume14pl
dc.identifier.doi10.1007/s11569-020-00377-1pl
dc.identifier.eissn1871-4765pl
dc.identifier.issn1871-4757pl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/258289
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa*
dc.rights.licenceCC-BY
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/legalcode.pl*
dc.share.typeinne
dc.subject.enoptogeneticspl
dc.subject.enmemory modification technologies (MMTs)pl
dc.subject.enmemorypl
dc.subject.enneuroethicspl
dc.subject.ensafetypl
dc.subject.enmoral obligationspl
dc.subject.enautonomypl
dc.subject.enexploitationpl
dc.subtypeArticlepl
dc.titleThe memory-modifying potential of optogenetics and the need for neuroethicspl
dc.title.journalNanoEthicspl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Optogenetics is an invasive neuromodulation technology involving the use of light to control the activity of individual neurons. Even though optogenetics is a relatively new neuromodulation tool whose various implications have not yet been scrutinized, it has already been approved for its first clinical trials in humans. As optogenetics is being intensively investigated in animal models with the aim of developing novel brain stimulation treatments for various neurological and psychiatric disorders, it appears crucial to consider both the opportunities and dangers such therapies may offer. In this review, we focus on the memory-modifying potential of optogenetics, investigating what it is capable of and how it differs from other memory modification technologies (MMTs). We then outline the safety challenges that need to be addressed before optogenetics can be used in humans. Finally, we re-examine crucial neuroethical concerns expressed in regard to other MMTs in the light of optogenetics and address those that appear to be unique to the memory-modifying potential of optogenetic technology.
dc.affiliationpl
Wydział Filozoficzny : Instytut Psychologii
dc.affiliationpl
Wydział Filozoficzny : Instytut Filozofii
dc.contributor.authorpl
Adamczyk, Agnieszka - 231689
dc.contributor.authorpl
Zawadzki, Przemysław - 221740
dc.date.accessioned
2020-12-06T21:50:08Z
dc.date.available
2020-12-06T21:50:08Z
dc.date.issuedpl
2020
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. 221-225. Autorka podpisana na pub.: Agnieszka K. Adamczyk
dc.description.numberpl
3
dc.description.physicalpl
207-225
dc.description.pointspl
70
dc.description.publicationpl
1
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
14
dc.identifier.doipl
10.1007/s11569-020-00377-1
dc.identifier.eissnpl
1871-4765
dc.identifier.issnpl
1871-4757
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/258289
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa
dc.rights.licence
CC-BY
dc.rights.uri*
http://creativecommons.org/licenses/by/4.0/legalcode.pl
dc.share.type
inne
dc.subject.enpl
optogenetics
dc.subject.enpl
memory modification technologies (MMTs)
dc.subject.enpl
memory
dc.subject.enpl
neuroethics
dc.subject.enpl
safety
dc.subject.enpl
moral obligations
dc.subject.enpl
autonomy
dc.subject.enpl
exploitation
dc.subtypepl
Article
dc.titlepl
The memory-modifying potential of optogenetics and the need for neuroethics
dc.title.journalpl
NanoEthics
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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