Wrażliwość na promieniowanie UVB u chorych na przewlekłe wirusowe zapalenie wątroby : badanie pilotażowe

2008
journal article
article
dc.abstract.enAbout 3% of the Polish population suffer from chronic viral hepatitis (CVH). CVH can be present without any symptoms. Some patients manifest only extrahepatic involvement during the course of hepatitis. CVH can present with symptoms of photosensitive diseases such as LE, DM, and PCT. The aim of the study was to assess UVB sensitivity in CVH patients in comparison with lupus erythematosus (LE) patients and healthy volunteers (HV). The study group consisted of 90 patients: 30 with CVH, 30 with LE and 30 HV. We performed phototesting in NB and BB UVB radiation and determined MED and the >1 MED erythema duration. A significant difference (p=0.01) was found between mean MED BB and NB UVB in subjects with LE and HV. Mean persistence time of >1 MED erythema was significantly different between LE patients and HV ($p<10^{-6}$) and between CVH and HV ($p<10^{-6}$). There were no significant differences in phototesting values between patients with CVH type B and CVH type C, between patients with normal or higher aminotransferase activity and between patients treated or untreated.: Our study revealed increased photosensitivity in CVH patients, especially in persistence of >1 MED erythema. This value was similar as in LE patients. There were no correlations between virus type, liver enzymes activity, treatment and phototesting results. Photosensitivity could be one of the extrahepatic manifestations of CVH.pl
dc.affiliationWydział Fizyki, Astronomii i Informatyki Stosowanej : Instytut Informatyki Stosowanejpl
dc.affiliationWydział Lekarski : Klinika Gastroenterologii i Hepatologiipl
dc.affiliationWydział Lekarski : Klinika Dermatologiipl
dc.contributor.authorWojas-Pelc, Anna - 133808 pl
dc.contributor.authorWęgrzyn, Edytapl
dc.contributor.authorKulig, Piotrpl
dc.contributor.authorMach, Tomasz - 130768 pl
dc.contributor.authorGłowacki, Mikołaj - 148277 pl
dc.contributor.authorSurówka, Grzegorz - 100453 pl
dc.date.accession2020-06-08pl
dc.date.accessioned2020-06-08T12:31:56Z
dc.date.available2020-06-08T12:31:56Z
dc.date.issued2008pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. 212-213pl
dc.description.number5pl
dc.description.physical206-213pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume25pl
dc.identifier.eissn2299-0046pl
dc.identifier.issn1642-395Xpl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/157209
dc.identifier.weblinkhttps://www.termedia.pl/Original-paper-UVB-sensitivity-in-chronic-viral-hepatitis-8211-pilot-study,7,11353,0,1.htmlpl
dc.languagepolpl
dc.language.containerpolpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-SA
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enchronic viral hepatitispl
dc.subject.enextrahepatic manifestationspl
dc.subject.enphotosensitivitypl
dc.subject.plprzewlekłe wirusowe zapalenie wątrobypl
dc.subject.plpozawątrobowe objawy zakażeniapl
dc.subject.plfotonadwrażliwośćpl
dc.subtypeArticlepl
dc.titleWrażliwość na promieniowanie UVB u chorych na przewlekłe wirusowe zapalenie wątroby : badanie pilotażowepl
dc.title.alternativeUVB sensitivity in chronic viral hepatitis : pilot studypl
dc.title.journalPostępy Dermatologii i Alergologiipl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
About 3% of the Polish population suffer from chronic viral hepatitis (CVH). CVH can be present without any symptoms. Some patients manifest only extrahepatic involvement during the course of hepatitis. CVH can present with symptoms of photosensitive diseases such as LE, DM, and PCT. The aim of the study was to assess UVB sensitivity in CVH patients in comparison with lupus erythematosus (LE) patients and healthy volunteers (HV). The study group consisted of 90 patients: 30 with CVH, 30 with LE and 30 HV. We performed phototesting in NB and BB UVB radiation and determined MED and the >1 MED erythema duration. A significant difference (p=0.01) was found between mean MED BB and NB UVB in subjects with LE and HV. Mean persistence time of >1 MED erythema was significantly different between LE patients and HV ($p<10^{-6}$) and between CVH and HV ($p<10^{-6}$). There were no significant differences in phototesting values between patients with CVH type B and CVH type C, between patients with normal or higher aminotransferase activity and between patients treated or untreated.: Our study revealed increased photosensitivity in CVH patients, especially in persistence of >1 MED erythema. This value was similar as in LE patients. There were no correlations between virus type, liver enzymes activity, treatment and phototesting results. Photosensitivity could be one of the extrahepatic manifestations of CVH.
dc.affiliationpl
Wydział Fizyki, Astronomii i Informatyki Stosowanej : Instytut Informatyki Stosowanej
dc.affiliationpl
Wydział Lekarski : Klinika Gastroenterologii i Hepatologii
dc.affiliationpl
Wydział Lekarski : Klinika Dermatologii
dc.contributor.authorpl
Wojas-Pelc, Anna - 133808
dc.contributor.authorpl
Węgrzyn, Edyta
dc.contributor.authorpl
Kulig, Piotr
dc.contributor.authorpl
Mach, Tomasz - 130768
dc.contributor.authorpl
Głowacki, Mikołaj - 148277
dc.contributor.authorpl
Surówka, Grzegorz - 100453
dc.date.accessionpl
2020-06-08
dc.date.accessioned
2020-06-08T12:31:56Z
dc.date.available
2020-06-08T12:31:56Z
dc.date.issuedpl
2008
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. 212-213
dc.description.numberpl
5
dc.description.physicalpl
206-213
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
25
dc.identifier.eissnpl
2299-0046
dc.identifier.issnpl
1642-395X
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/157209
dc.identifier.weblinkpl
https://www.termedia.pl/Original-paper-UVB-sensitivity-in-chronic-viral-hepatitis-8211-pilot-study,7,11353,0,1.html
dc.languagepl
pol
dc.language.containerpl
pol
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-SA
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-sa/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
chronic viral hepatitis
dc.subject.enpl
extrahepatic manifestations
dc.subject.enpl
photosensitivity
dc.subject.plpl
przewlekłe wirusowe zapalenie wątroby
dc.subject.plpl
pozawątrobowe objawy zakażenia
dc.subject.plpl
fotonadwrażliwość
dc.subtypepl
Article
dc.titlepl
Wrażliwość na promieniowanie UVB u chorych na przewlekłe wirusowe zapalenie wątroby : badanie pilotażowe
dc.title.alternativepl
UVB sensitivity in chronic viral hepatitis : pilot study
dc.title.journalpl
Postępy Dermatologii i Alergologii
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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