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Surface-enhanced Raman scattering study of the binding modes of a dibenzotetraaza[14]annulene derivative with DNA/RNA polynucleotides
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Surface-enhanced Raman scattering study of the binding modes of a dibenzotetraaza[14]annulene derivative with DNA/RNA polynucleotides
Bibliographic description
| title: | Surface-enhanced Raman scattering study of the binding modes of a dibenzotetraaza[14]annulene derivative with DNA/RNA polynucleotides |
| author: | Miljanić Snežana, Dijanošić Adriana, Kalac Matea, Radić Stojković Marijana, Piantanida Ivo, Pawlica Dariusz, Eilmes Julita 
|
| journal title: | Croatica Chemica Acta |
| volume: | 85 |
| issue: | 4 |
| date of publication : | 2012 |
| pages: | 577-584 |
| ISSN: |
0011-1643 |
| eISSN: |
1334-417X |
| DOI: | |
| URL: |
https://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=139013 |
| date accessed: |
2019-01-22 |
| notes: | Dariusz Pawlica - Instytut Chemii. |
| language: | English |
| journal language: | English |
| abstract in English: | Binding modes of a dibenzotetraaza[14]annulene (DBTAA) derivative with synthetic nucleic acids were studied using surface-enhanced Raman spectroscopy (SERS). Changes in SERS intensity and appearance of new bands in spectra were attributed to different complexes formed between the DBTAA molecules and DNA/RNA polynucleotides. A decrease in intensity pointed to intercalation as the dominant binding mode of the annulene derivative with poly dGdC-poly dGdC and poly rA-poly rU, whereas new bands in the spectra at 735 cm−1 and 1345 cm−1 revealed binding within the minor groove of poly dAdT-poly dAdT. When all the dominant binding sites were occupied, SERS spectra implied that small molecules bind on the outside of the DNA analogues, while exist mainly as free molecules in equimolar ratio with the synthetic RNA polynucleotide, thereby indicating higher affinity for DNA than for RNA. |
| keywords in English: | surface-enhanced Raman scattering, polynucleotide, binding, annulene |
| affiliation: | Wydział Chemii : Zakład Chemii Organicznej |
| type: | journal article |
| subtype: | academic paper |
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Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa
Projekt „Repozytorium otwartego dostępu do dorobku naukowego i dydaktycznego UJ” współfinansowany w ramach poddziałania 2.3.1 „Cyfrowe udostępnianie zasobów nauki” Programu Operacyjnego Polska Cyfrowa z Europejskiego Funduszu Rozwoju Regionalnego i budżetu państwa na podstawie umowy o dofinansowanie nr POPC.02.03.01-00-0030/17-00
