Nocebo hyperalgesia can be induced by classical conditioning without involvement of expectancy

2020
journal article
article
17
dc.abstract.enInfluential theoretical accounts take the position that classical conditioning can induce placebo effects through conscious expectancies. In the current study two different conditioning procedures (hidden and open) were used to separate expectancy from conditioning in order to reveal the role of expectancy in the formation of nocebo hyperalgesia. Eighty-seven healthy females were randomly assigned to three groups (hidden conditioning, open conditioning, and control). Participants were selected according to the Fear of Pain Questionnaire scores and assigned to two subgroups: high and low level of fear of pain (trait). They received electrocutaneous pain stimuli preceded by either an orange or blue color. During the conditioning phase, one color was paired with pain stimuli of moderate intensity (control stimuli) and the other color was paired with pain stimuli of high intensity (nocebo stimuli) in both hidden and open conditioning groups. Only participants in the open conditioning group were informed about this association, however just before the testing phase the expectancy of hyperalgesia induced in this way was withdrawn. In the control group, both colors were followed by control pain stimuli. During the testing phase all participants received a series of stimuli of the same intensity, regardless of the preceding color. Participants rated pain intensity, expectancy of pain intensity and fear (state). We found that nocebo hyperalgesia was induced by hidden rather than open conditioning. The hidden conditioning procedure did not produce conscious expectancies related to pain. Nocebo hyperalgesia was induced in participants with low and high fear of pain and there was no difference in the magnitude of the nocebo effect between both groups. Nocebo hyperalgesia was not predicted by the fear of upcoming painful stimuli.pl
dc.affiliationWydział Filozoficzny : Instytut Psychologiipl
dc.contributor.authorBajcar, Elżbieta - 361635 pl
dc.contributor.authorAdamczyk, Wacław M.pl
dc.contributor.authorWiercioch-Kuzianik, Karolina - 192998 pl
dc.contributor.authorBąbel, Przemysław - 127263 pl
dc.date.accession2020-05-10pl
dc.date.accessioned2020-05-20T17:24:34Z
dc.date.available2020-05-20T17:24:34Z
dc.date.issued2020pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.number5pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume15pl
dc.identifier.articleide0232108pl
dc.identifier.doi10.1371/journal.pone.0232108pl
dc.identifier.eissn1932-6203pl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/156221
dc.identifier.weblinkhttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0232108pl
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa*
dc.rights.licenceCC-BY
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subtypeArticlepl
dc.titleNocebo hyperalgesia can be induced by classical conditioning without involvement of expectancypl
dc.title.journalPLoS ONEpl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
Influential theoretical accounts take the position that classical conditioning can induce placebo effects through conscious expectancies. In the current study two different conditioning procedures (hidden and open) were used to separate expectancy from conditioning in order to reveal the role of expectancy in the formation of nocebo hyperalgesia. Eighty-seven healthy females were randomly assigned to three groups (hidden conditioning, open conditioning, and control). Participants were selected according to the Fear of Pain Questionnaire scores and assigned to two subgroups: high and low level of fear of pain (trait). They received electrocutaneous pain stimuli preceded by either an orange or blue color. During the conditioning phase, one color was paired with pain stimuli of moderate intensity (control stimuli) and the other color was paired with pain stimuli of high intensity (nocebo stimuli) in both hidden and open conditioning groups. Only participants in the open conditioning group were informed about this association, however just before the testing phase the expectancy of hyperalgesia induced in this way was withdrawn. In the control group, both colors were followed by control pain stimuli. During the testing phase all participants received a series of stimuli of the same intensity, regardless of the preceding color. Participants rated pain intensity, expectancy of pain intensity and fear (state). We found that nocebo hyperalgesia was induced by hidden rather than open conditioning. The hidden conditioning procedure did not produce conscious expectancies related to pain. Nocebo hyperalgesia was induced in participants with low and high fear of pain and there was no difference in the magnitude of the nocebo effect between both groups. Nocebo hyperalgesia was not predicted by the fear of upcoming painful stimuli.
dc.affiliationpl
Wydział Filozoficzny : Instytut Psychologii
dc.contributor.authorpl
Bajcar, Elżbieta - 361635
dc.contributor.authorpl
Adamczyk, Wacław M.
dc.contributor.authorpl
Wiercioch-Kuzianik, Karolina - 192998
dc.contributor.authorpl
Bąbel, Przemysław - 127263
dc.date.accessionpl
2020-05-10
dc.date.accessioned
2020-05-20T17:24:34Z
dc.date.available
2020-05-20T17:24:34Z
dc.date.issuedpl
2020
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.numberpl
5
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
15
dc.identifier.articleidpl
e0232108
dc.identifier.doipl
10.1371/journal.pone.0232108
dc.identifier.eissnpl
1932-6203
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/156221
dc.identifier.weblinkpl
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0232108
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa
dc.rights.licence
CC-BY
dc.rights.uri*
http://creativecommons.org/licenses/by/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subtypepl
Article
dc.titlepl
Nocebo hyperalgesia can be induced by classical conditioning without involvement of expectancy
dc.title.journalpl
PLoS ONE
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

* The migration of download and view statistics prior to the date of April 8, 2024 is in progress.

Views
17
Views per month
Views per city
Ashburn
3
Wroclaw
2
Chandler
1
Dublin
1
North Bergen
1
Shanghai
1
Downloads
bajcar_adamczyk_wiercioch-kuzianik_babel_nocebo_hyperalgesia_can_be_induced_2020.pdf
31
bajcar_adamczyk_wiercioch-kuzianik_babel_nocebo_hyperalgesia_can_be_induced_2020.odt
8