According to the fuzzy oil drop model, information required for complexation of an external polypeptide chain should be encoded as a local exposure of hydrophobicity on the protein surface. Of course, this is not the sole mechanism by which protein complexes may emerge; however, exposed hydrophobicity appears to play an important part in the complexation process. A local excess of hydrophobicity – especially if occurring on the surface – creates an environment which favors interaction with other polypeptide chains; particularly those, which also expose a hydrophobic interface.