2D IR correlation analysis of chitosan-MMT nanocomposite system
author:
Wesełucha-Birczyńska Aleksandra , Paluszkiewicz Czesława, Stodolak-Zych Ewa, Hasik Magdalena
journal title:
Vibrational Spectroscopy
title of volume:
Selected Papers from the 6th International Conference on Advanced Vibrational Spectroscopy (ICAVS-6) and Two-Dimensional Correlation Spectroscopy (2DCOS-6) Sonoma County, CA, USA, 9–17th June 2011
Novel materials for regenerative medicine are usually composites or nanocomposites. Their main task is
to stimulate damaged tissue for faster regeneration caused by enhanced activity of cells prone to intense
proliferation within the defect area. One of the main requirements for such materials is bioactivity,
which accelerates fixation between the material and surrounding tissue. After implanting into the body,
bioactive materials create new physicochemical bonds between the material and the surrounding tissue.
In their case apatite layers are formed on the implant surface without inducing growth of fibrous tissue
around them.
Some differences in bioactivity phenomena observed on the surface of materials depend on the mech-
anism of bonding and/or time required to create a new bonding and its strength. In the case of some
polymers, especially with highly porous or fibrous structures, the bioactivity phenomenon is initiated by
local increase in concentration of calcium and phosphate ions which become nuclei of apatite crystal-
lization.
Theworkpresentstime-dependentresultsofinteractionsbetweennanocompositefoilsandsimulation
body fluid solution (SBF). Nanocomposite foils were produced from chitosan (CS) and montmorillonite
(MMT). The obtained foils, CS and CSM (CS+MMT) were subjected to bioactivity tests by incubation in
SBF for different time. FTIR measurements were carried out on an Excalibur spectrometer using ATR
method in the wave number region from 550cm
−
1
to 4000cm
−
1
. The reaction between foils and SBF
was analyzed by 2D IR correlation spectroscopy The data obtained show local supersaturation of some
characteristic groups in CS-MMT material which seems to be the result of apatite nucleation.