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Effect of diabetes mellitus on clinical outcomes and quality of life after transcatheter aortic valve implantation for severe aortic valve stenosis
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Effect of diabetes mellitus on clinical outcomes and quality of life after transcatheter aortic valve implantation for severe aortic valve stenosis
Bibliographic description
| title: | Effect of diabetes mellitus on clinical outcomes and quality of life after transcatheter aortic valve implantation for severe aortic valve stenosis |
| author: | Tokarek Tomasz  , Dziewierz Artur , Wiktorowicz Agata, Bagienski Maciej, Rzeszutko Łukasz, Sorysz Danuta, Kleczyński Paweł , Dudek Dariusz
|
| journal title: | Hellenic Journal of Cardiology |
| volume: | 59 |
| issue: | 2 |
| date of publication : | 2018 |
| pages: | 100-107 |
| ISSN: |
1109-9666 |
| eISSN: |
2241-5955 |
| DOI: | |
| language: | English |
| journal language: | English |
| abstract in English: | Background: Diabetes mellitus (DM) is considered a marker of poor prognosis after cardiac surgery. We sought to investigate the effect of DM on clinical outcomes and quality of life (QoL) after transcatheter aortic valve implantation (TAVI). Methods: A total of 148 consecutive patients with symptomatic, severe aortic stenosis who underwent TAVI were included. Baseline characteristics, procedural and long-term clinical outcomes, and the results of frailty and QoL assessment with EQ-5D-3L questionnaire were compared between patients with and without DM. Results: DM was present in 48 of 148 (32.4%) patients. No differences in periprocedural risk (Logistic Euroscore and Society of Thoracic Surgeons (STS) scale) between groups were observed. There were no differences in 30-day and 12-month all-cause mortality between groups [DM( ) vs. DM(þ): 7 (7.0%) vs. 5 (10.4%), p Z 0.53 and 12 (12.0%) vs. 10 (20.8%), p Z 0.16, respectively]. No influence of DM presence on the risk of death was confirmed after adjustment for age and gender (for 30-day mortality, age/gender-adjusted OR 1.55, 95%CI 0.47 e5.17; for 12-month mortality, age/gender-adjusted OR 2.05, 95%CI 0.79e5.32). Similarly, at the longest available follow-up, mortality did not differ between groups [14 (29.2%) vs. 19 (19.0%), p Z 0.16; age/gender-adjusted OR 1.81, 95%CI 0.80e4.08]. Similar rates of other complications after TAVI were noted. Frailty measured with the 5-meter walking test was more frequently reported in patients with DM [11 (22.9%) vs. 10 (10.0%), p Z 0.035]. No differences in QoL parameters at baseline and 12 months were noted. Conclusions: Patients with DM undergoing TAVI demonstrated similar mortality, complication rates, and QoL outcomes compared to patients without DM |
| keywords in English: | frailty, transcatheter aortic valve replacement, aortic valve disease, high-risk patients, registry |
| departmental parameterization: | 20 |
| affiliation: | Wydział Lekarski : Instytut Kardiologii |
| type: | journal article |
| subtype: | academic paper |
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Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
Projekt „Repozytorium otwartego dostępu do dorobku naukowego i dydaktycznego UJ” współfinansowany w ramach poddziałania 2.3.1 „Cyfrowe udostępnianie zasobów nauki” Programu Operacyjnego Polska Cyfrowa z Europejskiego Funduszu Rozwoju Regionalnego i budżetu państwa na podstawie umowy o dofinansowanie nr POPC.02.03.01-00-0030/17-00
