Jagiellonian University Repository
Impact of postoperative bleeding on short-term outcome in patients after orthotopic heart transplantation : a retrospective cohort study
Communities & Collections
pcg.skipToMenu
Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
Impact of postoperative bleeding on short-term outcome in patients after orthotopic heart transplantation : a retrospective cohort study
Bibliographic description
| title: | Impact of postoperative bleeding on short-term outcome in patients after orthotopic heart transplantation : a retrospective cohort study |
| author: | Kędziora Anna  , Wierzbicki Karol , Mazur Piotr , Song Bryan HyoChan, Piątek Jacek, Milaniak Irena, Węgrzyn Piotr, Kapelak Bogusław , Drwiła Rafał , Sobczyk Dorota , Górkiewicz-Kot Izabela, Bartuś Krzysztof , Niekowal Bogdan , Sadowski Jerzy
|
| journal title: | Annals of Transplantation |
| volume: | 21 |
| issue: | 1 |
| date of publication : | 2016 |
| pages: | 689-694 |
| ISSN: |
1425-9524 |
| eISSN: |
2329-0358 |
| DOI: | |
| language: | English |
| abstract in English: | BACKGROUND: Orthotopic heart transplantation (HTX) remains the ultimate treatment option in patients with end-stage heart failure, endorsed by the European Society of Cardiology guidelines. The aim of the study is a complex evaluation of the postoperative bleeding after HTX and its influence on short-term outcome. MATERIAL AND METHODS: A retrospective cohort study consisted of 53 patients (4 females and 49 males, median age 52.5 years, IQR 17 years) who underwent HTX in the Department of Cardiovascular Surgery and Transplantology of John Paul II Hospital in Krakow between 2007 and 2014. RESULTS: The median chest tube output within first 24 hours after the surgery was 695 (550–870) mL. Bleeding decreased throughout the observation (p=0.000). The first postoperative hemoglobin level was a significant predictor of excessive blood loss (p=0.017). The volume of chest tube output increased the duration of mechanical ventilation (p=0.046) and the incidence of re-exploration after first 24 hours of observation (p=0.049). In patients with higher chest tube output, more packed red blood cells (PRBC), fresh frozen plasma (FFP), and platelet (PLT) transfusions were required (p=0.000, p=0.019, and p=0.000, respectively). Early rethoracotomy (within the first 24 hours post-surgery) increased the in-hospital mortality (p=0.021; OR 7.43 [1.36–40.64]). CONCLUSIONS: The study demonstrates the importance of postoperative bleeding and bleeding complications for short-term outcome in our post-HTX cohort. Throughout the analysis, the first postoperative hemoglobin level was detected to be a significant predictor of postoperative blood loss. |
| keywords in English: | chest tubes, erythrocyte transfusion, heart transplantation, postoperative hemorrhage, treatment outcome |
| departmental parameterization: | 20 |
| affiliation: | Wydział Lekarski : Instytut Kardiologii, Wydział Lekarski : Zakład Anestezjologii i Intensywnej Terapii, Wydział Lekarski : I Katedra Chirurgii Ogólnej |
| type: | journal article |
| subtype: | academic paper |
Files in this item
This item appears in the following Collection(s)
Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
Projekt „Repozytorium otwartego dostępu do dorobku naukowego i dydaktycznego UJ” współfinansowany w ramach poddziałania 2.3.1 „Cyfrowe udostępnianie zasobów nauki” Programu Operacyjnego Polska Cyfrowa z Europejskiego Funduszu Rozwoju Regionalnego i budżetu państwa na podstawie umowy o dofinansowanie nr POPC.02.03.01-00-0030/17-00
