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Progestogens in menopausal hormone therapy
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Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa
Progestogens in menopausal hormone therapy
Bibliographic description
| title: | Progestogens in menopausal hormone therapy |
| author: | Bińkowska Małgorzata, Woroń Jarosław 
|
| journal title: | Przegląd Menopauzalny |
| volume: | 14 |
| issue: | 2 |
| date of publication : | 2015 |
| pages: | 134-143 |
| ISSN: |
1643-8876 |
| eISSN: |
2299-0038 |
| DOI: | |
| language: | English |
| journal language: | Polish |
| abstract in English: | Progestogens share one common effect: the ability to convert proliferative endometrium to its secretory form. In contrast, their biological activity is varied, depending on the chemical structure, pharmacokinetics, receptor affinity and different potency of action. Progestogens are widely used in the treatment of menstrual cycle disturbances, various gynaecological conditions, contraception and menopausal hormone therapy. The administration of progestogen in menopausal hormone therapy is essential in women with an intact uterus to protect against endometrial hyperplasia and cancer. Progestogen selection should be based on the characteristics available for each progestogen type, relying on the assessment of relative potency of action in experimental models and animal models, and on the indirect knowledge brought by studies of the clinical use of different progestogen formulations. The choice of progestogen should involve the conscious use of knowledge of its benefits, with a focus on minimizing potential side effects. Unfortunately, there are no direct clinical studies comparing the metabolic effects of different progestogens. |
| keywords in English: | progestogens, menopausal hormone, therapy, progesterone, progestin |
| departmental parameterization: | 8 |
| affiliation: | Wydział Lekarski : Zakład Farmakologii Klinicznej |
| type: | journal article |
| subtype: | review article |
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Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Na tych samych warunkach 4.0 Międzynarodowa
Projekt „Repozytorium otwartego dostępu do dorobku naukowego i dydaktycznego UJ” współfinansowany w ramach poddziałania 2.3.1 „Cyfrowe udostępnianie zasobów nauki” Programu Operacyjnego Polska Cyfrowa z Europejskiego Funduszu Rozwoju Regionalnego i budżetu państwa na podstawie umowy o dofinansowanie nr POPC.02.03.01-00-0030/17-00
