Preoperative embolisation of renal cell carcinoma metastases to the spine : evaluation of procedural and clinical outcome

2024
journal article
article
dc.abstract.enPurpose: Renal cell carcinoma (RCC) is the fourth most common metastatic tumour of the spine. RCC metastases are highly vascular and might cause life-threatening intraoperative bleeding. That is why preoperative embolisation is performed to reduce intraoperative blood loss. The aim of this study was to evaluate the procedural and clinical outcomes of preoperative embolisation of RCC metastases to the vertebral column. Material and methods: In this single-centre retrospective study, data of 59 consecutive patients undergoing endovascular treatment prior to surgical resection were collected and evaluated. In all cases superselective catheterisation and occlusion of feeding vessels was attempted and performed if deemed safe and possible. Completeness of embolisation, procedural details, and the complication rate were evaluated. Surgical procedures were carried out within 48 hours after embolisation. The surgical approach was dependent on the anatomical site and osseous destruction. Intraoperative blood loss was estimated. Results: Fifty-nine patients with a mean age of 63 years were included. Complete embolisation was successful in 76% (45/59) and partial in 15% (9/59). Microspheres were the most commonly used embolic material. In 5 cases (8%) safe occlusion was not possible due to the radiculomedullary artery originating from the same pedicle as the tumour. Minor complications (vomiting, increased pain) occurred in 8 patients. Paraplegia (one transient and one permanent) was noted in 2 cases. Estimated intraoperative blood loss was 830 ± 410 ml. Conclusions: The results of our study show that preoperative embolisation is a feasible and effective method with a relatively high rate of occlusion and low complication rate.
dc.contributor.authorSzmygin, Paweł
dc.contributor.authorSzmygin, Maciej
dc.contributor.authorPyra, Krzysztof
dc.contributor.authorRogała, Władysław
dc.contributor.authorAndrzejewicz, Paweł
dc.contributor.authorJargiełło, Tomasz
dc.date.accessioned2025-07-25T09:01:51Z
dc.date.available2025-07-25T09:01:51Z
dc.date.createdat2025-07-25T09:01:51Zen
dc.date.issued2024
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. e132-e133
dc.description.physicale128-e133
dc.description.versionostateczna wersja wydawcy
dc.description.volume89
dc.identifier.doi10.5114/pjr.2024.136398
dc.identifier.issn1733-134X
dc.identifier.projectDRC AI
dc.identifier.urihttps://ruj.uj.edu.pl/handle/item/558250
dc.languageeng
dc.language.containereng
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.typeotwarte czasopismo
dc.subject.enrenal cell carcinoma
dc.subject.enspinal metastases
dc.subject.enembolisation
dc.subject.enprocedural outcome
dc.subtypeArticle
dc.titlePreoperative embolisation of renal cell carcinoma metastases to the spine : evaluation of procedural and clinical outcome
dc.title.journalPolish Journal of Radiology
dc.typeJournalArticle
dspace.entity.typePublicationen
dc.abstract.en
Purpose: Renal cell carcinoma (RCC) is the fourth most common metastatic tumour of the spine. RCC metastases are highly vascular and might cause life-threatening intraoperative bleeding. That is why preoperative embolisation is performed to reduce intraoperative blood loss. The aim of this study was to evaluate the procedural and clinical outcomes of preoperative embolisation of RCC metastases to the vertebral column. Material and methods: In this single-centre retrospective study, data of 59 consecutive patients undergoing endovascular treatment prior to surgical resection were collected and evaluated. In all cases superselective catheterisation and occlusion of feeding vessels was attempted and performed if deemed safe and possible. Completeness of embolisation, procedural details, and the complication rate were evaluated. Surgical procedures were carried out within 48 hours after embolisation. The surgical approach was dependent on the anatomical site and osseous destruction. Intraoperative blood loss was estimated. Results: Fifty-nine patients with a mean age of 63 years were included. Complete embolisation was successful in 76% (45/59) and partial in 15% (9/59). Microspheres were the most commonly used embolic material. In 5 cases (8%) safe occlusion was not possible due to the radiculomedullary artery originating from the same pedicle as the tumour. Minor complications (vomiting, increased pain) occurred in 8 patients. Paraplegia (one transient and one permanent) was noted in 2 cases. Estimated intraoperative blood loss was 830 ± 410 ml. Conclusions: The results of our study show that preoperative embolisation is a feasible and effective method with a relatively high rate of occlusion and low complication rate.
dc.contributor.author
Szmygin, Paweł
dc.contributor.author
Szmygin, Maciej
dc.contributor.author
Pyra, Krzysztof
dc.contributor.author
Rogała, Władysław
dc.contributor.author
Andrzejewicz, Paweł
dc.contributor.author
Jargiełło, Tomasz
dc.date.accessioned
2025-07-25T09:01:51Z
dc.date.available
2025-07-25T09:01:51Z
dc.date.createdaten
2025-07-25T09:01:51Z
dc.date.issued
2024
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additional
Bibliogr. s. e132-e133
dc.description.physical
e128-e133
dc.description.version
ostateczna wersja wydawcy
dc.description.volume
89
dc.identifier.doi
10.5114/pjr.2024.136398
dc.identifier.issn
1733-134X
dc.identifier.project
DRC AI
dc.identifier.uri
https://ruj.uj.edu.pl/handle/item/558250
dc.language
eng
dc.language.container
eng
dc.rights
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.en
renal cell carcinoma
dc.subject.en
spinal metastases
dc.subject.en
embolisation
dc.subject.en
procedural outcome
dc.subtype
Article
dc.title
Preoperative embolisation of renal cell carcinoma metastases to the spine : evaluation of procedural and clinical outcome
dc.title.journal
Polish Journal of Radiology
dc.type
JournalArticle
dspace.entity.typeen
Publication
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