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A vision to increase the availability of PET diagnosis in low- and medium-income countries by combining a low-cost modular J-PET tomograph with the
positron emission tomography
PET
modular J-PET
scandium
Objectives: This paper presents the prospects for increasing the availability of PET diagnostics by combining low-cost, lightweight and easily portable modular J-PET with the
dc.abstract.en | Objectives: This paper presents the prospects for increasing the availability of PET diagnostics by combining low-cost, lightweight and easily portable modular J-PET with the $^{44}$Ti/$^{44}$Sc generator. Methods: J-PET is constructed based on the low-cost axially arranged plastic scintillators that may enable the construction of PET scanners 5 to 10 times less expensive compared to current PET systems, which are based on crystal scintillators. Development of the radionuclide $^{44}$Ti/$^{44}$Sc generator with the 60-year half-lifetime would enable long-term onsite production of $^{44}$Sc labelled radiopharmaceuticals, eliminating the need for extensive and costly infrastructure typically associated with nuclear medicine. Presently applied $^{68}$Ge/$^{68}$Ga generators with the 270 days half- -lifetime require renewal every year. The $^{44}$Ti/$^{44}$Sc generator could, in principle, be purchased once every half century. Results: The lightweight and portable J-PET scanner, combined with the $^{44}$Ti/$^{44}$Sc generator, can be deployed in remote and underserved regions, thus democratising access to advanced medical-imaging techniques. Conclusions: This novel concept shows the transformative potential of combining innovative J-PET technology with the $^{44}$Ti/$^{44}$Sc generator to make advanced diagnostics more accessible and affordable worldwide, especially benefiting millions of patients in low- and medium-income countries, and driving further innovations in medical imaging. | |
dc.affiliation | Wydział Fizyki, Astronomii i Informatyki Stosowanej : Instytut Fizyki im. Mariana Smoluchowskiego | |
dc.contributor.author | Moskal, Paweł - 100401 | |
dc.contributor.author | Stępień, Ewa - 161583 | |
dc.contributor.author | Khreptak, Aleksander - 262561 | |
dc.date.accessioned | 2025-02-04T15:02:55Z | |
dc.date.available | 2025-02-04T15:02:55Z | |
dc.date.createdat | 2025-02-03T10:15:05Z | en |
dc.date.issued | 2024 | |
dc.date.openaccess | 0 | |
dc.description.accesstime | w momencie opublikowania | |
dc.description.number | Special Issue | |
dc.description.physical | 55-62 | |
dc.description.version | ostateczna wersja wydawcy | |
dc.description.volume | 20 | |
dc.identifier.doi | 10.5604/01.3001.0054.9273 | |
dc.identifier.eissn | 1896-530X | |
dc.identifier.issn | 1895-9091 | |
dc.identifier.uri | https://ruj.uj.edu.pl/handle/item/547005 | |
dc.language | eng | |
dc.language.container | eng | |
dc.rights | Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa | |
dc.rights.licence | CC-BY | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/legalcode.pl | |
dc.share.type | otwarte czasopismo | |
dc.subject.en | positron emission tomography | |
dc.subject.en | PET | |
dc.subject.en | modular J-PET | |
dc.subject.en | scandium | |
dc.subject.en | $^{44}$Ti/$^{44}$Sc generator | |
dc.subtype | Article | |
dc.title | A vision to increase the availability of PET diagnosis in low- and medium-income countries by combining a low-cost modular J-PET tomograph with the $^{44}$Ti/$^{44}$Sc generator | |
dc.title.journal | Bio-Algorithms and Med-Systems | |
dc.type | JournalArticle | |
dspace.entity.type | Publication | en |