Białko S100B, astrocyty i pamięć

2008
journal article
article
dc.abstract.enS100 is a vertebrate-specific family of small, calcium-binding proteins. One of them is the S100B protein, mostly expressed in, and released by astroglial cells in the brain. The protein has been implicated in the regulation of numerous processes including phosphorylation of cytoskeletal proteins, cell proliferation and differentiation, as well as many other functions. This article focuses on the role of S100B in processes relating to learning and memory. More than four decades of behavioral and neurophysiological research have revealed beneficial effects of this protein. However, there is also evidence suggesting that overexpression of S100B can lead to memory dysfunction. It is possible that an increased S100B release from astrocytes may be co-responsible for memory dysfunction observed in the early stages of Alzheimer's disease.pl
dc.affiliationWydział Biologii i Nauk o Ziemi : Instytut Zoologiipl
dc.contributor.authorKiełbiński, Michał - 104303 pl
dc.contributor.authorSołtys, Zbigniew - 147734 pl
dc.date.accessioned2016-09-27T13:28:39Z
dc.date.available2016-09-27T13:28:39Z
dc.date.issued2008pl
dc.date.openaccess144
dc.description.accesstimepo opublikowaniu
dc.description.number1pl
dc.description.physical1-11pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume35pl
dc.identifier.doi10.2478/v100052-008-0005pl
dc.identifier.eissn2080-2218pl
dc.identifier.issn0324-833Xpl
dc.identifier.projectROD UJ / Spl
dc.identifier.urihttp://ruj.uj.edu.pl/xmlui/handle/item/30851
dc.languageengpl
dc.language.containerengpl
dc.rightsDozwolony użytek utworów chronionych*
dc.rights.licenceOTHER
dc.rights.urihttp://ruj.uj.edu.pl/4dspace/License/copyright/licencja_copyright.pdf*
dc.share.typeotwarte repozytorium
dc.subject.enS100B proteinpl
dc.subject.encytoskeletonpl
dc.subject.enmemorypl
dc.subject.enastrocytespl
dc.subject.plbiałko S100Bpl
dc.subject.plcytoszkieletpl
dc.subject.plastrocytypl
dc.subject.plpamięćpl
dc.subtypeArticlepl
dc.titleBiałko S100B, astrocyty i pamięćpl
dc.title.alternativeS100B protein, astrocytes and memorypl
dc.title.journalPostępy Biologii Komórkipl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.enpl
S100 is a vertebrate-specific family of small, calcium-binding proteins. One of them is the S100B protein, mostly expressed in, and released by astroglial cells in the brain. The protein has been implicated in the regulation of numerous processes including phosphorylation of cytoskeletal proteins, cell proliferation and differentiation, as well as many other functions. This article focuses on the role of S100B in processes relating to learning and memory. More than four decades of behavioral and neurophysiological research have revealed beneficial effects of this protein. However, there is also evidence suggesting that overexpression of S100B can lead to memory dysfunction. It is possible that an increased S100B release from astrocytes may be co-responsible for memory dysfunction observed in the early stages of Alzheimer's disease.
dc.affiliationpl
Wydział Biologii i Nauk o Ziemi : Instytut Zoologii
dc.contributor.authorpl
Kiełbiński, Michał - 104303
dc.contributor.authorpl
Sołtys, Zbigniew - 147734
dc.date.accessioned
2016-09-27T13:28:39Z
dc.date.available
2016-09-27T13:28:39Z
dc.date.issuedpl
2008
dc.date.openaccess
144
dc.description.accesstime
po opublikowaniu
dc.description.numberpl
1
dc.description.physicalpl
1-11
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
35
dc.identifier.doipl
10.2478/v100052-008-0005
dc.identifier.eissnpl
2080-2218
dc.identifier.issnpl
0324-833X
dc.identifier.projectpl
ROD UJ / S
dc.identifier.uri
http://ruj.uj.edu.pl/xmlui/handle/item/30851
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Dozwolony użytek utworów chronionych
dc.rights.licence
OTHER
dc.rights.uri*
http://ruj.uj.edu.pl/4dspace/License/copyright/licencja_copyright.pdf
dc.share.type
otwarte repozytorium
dc.subject.enpl
S100B protein
dc.subject.enpl
cytoskeleton
dc.subject.enpl
memory
dc.subject.enpl
astrocytes
dc.subject.plpl
białko S100B
dc.subject.plpl
cytoszkielet
dc.subject.plpl
astrocyty
dc.subject.plpl
pamięć
dc.subtypepl
Article
dc.titlepl
Białko S100B, astrocyty i pamięć
dc.title.alternativepl
S100B protein, astrocytes and memory
dc.title.journalpl
Postępy Biologii Komórki
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

* The migration of download and view statistics prior to the date of April 8, 2024 is in progress.

Views
3
Views per month
Views per city
Ashburn
2
Downloads
kielbinski_soltys_bialko_s100b_astrocyty_2008.pdf
22