Role of diffusion-weighted magnetic resonance imaging in the differentiation of benign and malignant pulmonary lesions

2018
journal article
article
4
cris.lastimport.wos2024-04-10T00:55:35Z
dc.abstract.enPurpose: To evaluate the role of magnetic resonance (MRI) diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) measurement of solid and cystic pulmonary masses in differentiating benign from malignant lesions. Material and methods: The study included 41 patients with pulmonary masses, who underwent conventional MRI and DWI (b value 0, 500, and 1000 s/mm²) examinations with 1.5-T MRI. The diffusion signal and the mean ADC values of the solid and cystic lesions were obtained. Statistical analyses were performed with the Mann-Whitney U test (z), Pearson's chi-square test, and receiver operating characteristic (ROC) analysis. Results: Thirty-three lesions were malignant, and eight lesions were benign. The malignant masses showed significantly higher signal intensity on DWI than benign masses (p = 0.006), and the mean ADC value of malignant solid lesions was significantly lower than that of benign lesions (p = 0.02). By ROC analysis, an ADC cut-off value of 1.4 × 10-3 mm2/s was considered the threshold value, and the sensitivity and specificity were 93.8% and 75%, respectively. There was no significant difference between the ADC value of the cystic parts inside the benign and the malignant lesions. Conclusions: Diffusion-weighted MRI and measurement of ADC value can significantly differentiate between solid benign and malignant pulmonary masses.pl
dc.contributor.authorAlnaghy, Eman Abdelazizpl
dc.contributor.authorEl-Nahas, Mahmoud Ahmedpl
dc.contributor.authorSadek, Ahmed Galalpl
dc.contributor.authorGwely, Noureldin Noamanpl
dc.contributor.authorElrakhawy, Mohamed Magdypl
dc.date.accessioned2019-02-19T13:05:03Z
dc.date.available2019-02-19T13:05:03Z
dc.date.issued2018pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. e594pl
dc.description.physicale585-e594pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume83pl
dc.identifier.doi10.5114/pjr.2018.81281pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.projectROD UJ / OPpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/68745
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.endiffusion MRIpl
dc.subject.enADCpl
dc.subject.enbenignpl
dc.subject.enmalignantpl
dc.subject.enpulmonary lesionspl
dc.subtypeArticlepl
dc.titleRole of diffusion-weighted magnetic resonance imaging in the differentiation of benign and malignant pulmonary lesionspl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-10T00:55:35Z
dc.abstract.enpl
Purpose: To evaluate the role of magnetic resonance (MRI) diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) measurement of solid and cystic pulmonary masses in differentiating benign from malignant lesions. Material and methods: The study included 41 patients with pulmonary masses, who underwent conventional MRI and DWI (b value 0, 500, and 1000 s/mm²) examinations with 1.5-T MRI. The diffusion signal and the mean ADC values of the solid and cystic lesions were obtained. Statistical analyses were performed with the Mann-Whitney U test (z), Pearson's chi-square test, and receiver operating characteristic (ROC) analysis. Results: Thirty-three lesions were malignant, and eight lesions were benign. The malignant masses showed significantly higher signal intensity on DWI than benign masses (p = 0.006), and the mean ADC value of malignant solid lesions was significantly lower than that of benign lesions (p = 0.02). By ROC analysis, an ADC cut-off value of 1.4 × 10-3 mm2/s was considered the threshold value, and the sensitivity and specificity were 93.8% and 75%, respectively. There was no significant difference between the ADC value of the cystic parts inside the benign and the malignant lesions. Conclusions: Diffusion-weighted MRI and measurement of ADC value can significantly differentiate between solid benign and malignant pulmonary masses.
dc.contributor.authorpl
Alnaghy, Eman Abdelaziz
dc.contributor.authorpl
El-Nahas, Mahmoud Ahmed
dc.contributor.authorpl
Sadek, Ahmed Galal
dc.contributor.authorpl
Gwely, Noureldin Noaman
dc.contributor.authorpl
Elrakhawy, Mohamed Magdy
dc.date.accessioned
2019-02-19T13:05:03Z
dc.date.available
2019-02-19T13:05:03Z
dc.date.issuedpl
2018
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. e594
dc.description.physicalpl
e585-e594
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
83
dc.identifier.doipl
10.5114/pjr.2018.81281
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.projectpl
ROD UJ / OP
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/68745
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
diffusion MRI
dc.subject.enpl
ADC
dc.subject.enpl
benign
dc.subject.enpl
malignant
dc.subject.enpl
pulmonary lesions
dc.subtypepl
Article
dc.titlepl
Role of diffusion-weighted magnetic resonance imaging in the differentiation of benign and malignant pulmonary lesions
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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