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Transcatheter aortic valve implantation and cardiac conduction abnormalities : prevalence, risk factors and management
transcatheter aortic valve implantation
TAVR
conduction abnormalities
atrioventricular block
left bundle branch block
cardiovascular implantable electronic devices
pacemaker implantation
arrhythmia
Over the last decades, transcatheter aortic valve implantation (TAVI) or replacement (TAVR) has become a potential, widely accepted, and effective method of treating aortic stenosis in patients at moderate and high surgical risk and those disqualified from surgery. The method evolved what translates into a noticeable decrease in the incidence of complications and more beneficial clinical outcomes. However, the incidence of conduction abnormalities related to TAVI, including left bundle branch block and complete or second-degree atrioventricular block (AVB), remains high. The occurrence of AVB requiring permanent pacemaker implantation is associated with a worse prognosis in this group of patients. The identification of risk factors for conduction disturbances requiring pacemaker placement and the assessment of their relation to pacing dependence may help to develop methods of optimal care, including preventive measures, for patients undergoing TAVI. This approach is crucial given the emerging evidence of no worse outcomes for intermediate and low-risk patients undergoing TAVI in comparison to surgical aortic valve replacement. This paper comprehensively discusses the mechanisms, risk factors, and consequences of conduction abnormalities and arrhythmias, including AVB, atrial fibrillation, and ventricular arrhythmias associated with aortic stenosis and TAVI, as well as provides insights into optimized patient care, along with the potential of conduction system pacing and cardiac resynchronization therapy, to minimize the risk of unfavorable clinical outcomes.
cris.lastimport.wos | 2024-04-10T00:51:43Z | |
dc.abstract.en | Over the last decades, transcatheter aortic valve implantation (TAVI) or replacement (TAVR) has become a potential, widely accepted, and effective method of treating aortic stenosis in patients at moderate and high surgical risk and those disqualified from surgery. The method evolved what translates into a noticeable decrease in the incidence of complications and more beneficial clinical outcomes. However, the incidence of conduction abnormalities related to TAVI, including left bundle branch block and complete or second-degree atrioventricular block (AVB), remains high. The occurrence of AVB requiring permanent pacemaker implantation is associated with a worse prognosis in this group of patients. The identification of risk factors for conduction disturbances requiring pacemaker placement and the assessment of their relation to pacing dependence may help to develop methods of optimal care, including preventive measures, for patients undergoing TAVI. This approach is crucial given the emerging evidence of no worse outcomes for intermediate and low-risk patients undergoing TAVI in comparison to surgical aortic valve replacement. This paper comprehensively discusses the mechanisms, risk factors, and consequences of conduction abnormalities and arrhythmias, including AVB, atrial fibrillation, and ventricular arrhythmias associated with aortic stenosis and TAVI, as well as provides insights into optimized patient care, along with the potential of conduction system pacing and cardiac resynchronization therapy, to minimize the risk of unfavorable clinical outcomes. | |
dc.affiliation | Wydział Lekarski : Instytut Kardiologii | pl |
dc.cm.date | 2023-10-29T23:18:33Z | |
dc.cm.id | 113536 | pl |
dc.cm.idOmega | UJCMd1bddac3d548420290ddce7c9b824159 | pl |
dc.contributor.author | Szotek, Michał | pl |
dc.contributor.author | Drużbicki, Łukasz | pl |
dc.contributor.author | Sabatowski, Karol | pl |
dc.contributor.author | Amoroso, Gisella R. | pl |
dc.contributor.author | De Schouwer, Koen | pl |
dc.contributor.author | Matusik, Paweł - 139227 | pl |
dc.date.accession | 2023-10-27 | pl |
dc.date.accessioned | 2023-10-29T23:18:33Z | |
dc.date.available | 2023-10-29T23:18:33Z | |
dc.date.issued | 2023 | pl |
dc.date.openaccess | 0 | |
dc.description.accesstime | w momencie opublikowania | |
dc.description.number | 18 | pl |
dc.description.version | ostateczna wersja wydawcy | |
dc.description.volume | 12 | pl |
dc.identifier.articleid | 6056 | pl |
dc.identifier.doi | 10.3390/jcm12186056 | pl |
dc.identifier.eissn | 2077-0383 | pl |
dc.identifier.issn | 2077-0383 | pl |
dc.identifier.uri | https://ruj.uj.edu.pl/xmlui/handle/item/322470 | |
dc.identifier.weblink | https://www.mdpi.com/2077-0383/12/18/6056 | pl |
dc.language | eng | pl |
dc.language.container | eng | pl |
dc.pbn.affiliation | Dziedzina nauk medycznych i nauk o zdrowiu : nauki medyczne | |
dc.rights | Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa | |
dc.rights.licence | CC-BY | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/legalcode.pl | |
dc.share.type | Otwarte czasopismo | |
dc.subject.en | transcatheter aortic valve implantation | |
dc.subject.en | TAVR | |
dc.subject.en | conduction abnormalities | |
dc.subject.en | atrioventricular block | |
dc.subject.en | left bundle branch block | |
dc.subject.en | cardiovascular implantable electronic devices | |
dc.subject.en | pacemaker implantation | |
dc.subject.en | arrhythmia | |
dc.subtype | ReviewArticle | pl |
dc.title | Transcatheter aortic valve implantation and cardiac conduction abnormalities : prevalence, risk factors and management | pl |
dc.title.journal | Journal of Clinical Medicine | pl |
dc.type | JournalArticle | pl |
dspace.entity.type | Publication |
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