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Positronium lifetime validation measurements using a long-axial field-of-view positron emission tomography scanner
positronium imaging
positron emission tomography
molecular imaging
Positron emission tomography (PET) traditionally uses coincident annihilation photons emitted from a positron interacting with an electron to localize cancer within the body. The formation of positronium (Ps), a bonded electron-positron pair, has not been utilized in clinical applications of PET due to the need to detect either the emission of a prompt gamma ray or the decay of higher-order coincident events. Assessment of the lifetime of the formed Ps, however, can potentially yield additional diagnostic information of the surrounding tissue because Ps properties vary due to void size and molecular composition. To assess the feasibility of measuring Ps lifetimes with a PET scanner, experiments were performed in a Biograph Vision Quadra (Siemens Healthineers). Quadra is a long-axial field-of-view (LA-FOV) PET scanner capable of producing list-mode data from single interaction events.
dc.abstract.en | Positron emission tomography (PET) traditionally uses coincident annihilation photons emitted from a positron interacting with an electron to localize cancer within the body. The formation of positronium (Ps), a bonded electron-positron pair, has not been utilized in clinical applications of PET due to the need to detect either the emission of a prompt gamma ray or the decay of higher-order coincident events. Assessment of the lifetime of the formed Ps, however, can potentially yield additional diagnostic information of the surrounding tissue because Ps properties vary due to void size and molecular composition. To assess the feasibility of measuring Ps lifetimes with a PET scanner, experiments were performed in a Biograph Vision Quadra (Siemens Healthineers). Quadra is a long-axial field-of-view (LA-FOV) PET scanner capable of producing list-mode data from single interaction events. | |
dc.affiliation | Szkoła Doktorska Nauk Ścisłych i Przyrodniczych | |
dc.affiliation | Wydział Fizyki, Astronomii i Informatyki Stosowanej : Instytut Fizyki im. Mariana Smoluchowskiego | |
dc.contributor.author | Steinberger, William M. | |
dc.contributor.author | Mercolli, Lorenzo | |
dc.contributor.author | Breuer, Johannes | |
dc.contributor.author | Sari, Hasan | |
dc.contributor.author | Parzych, Szymon - 369531 | |
dc.contributor.author | Niedźwiecki, Szymon - 115136 | |
dc.contributor.author | Lapkiewicz, Gabriela | |
dc.contributor.author | Moskal, Paweł - 100401 | |
dc.contributor.author | Stępień, Ewa - 161583 | |
dc.contributor.author | Rominger, Axel | |
dc.contributor.author | Shi, Kuangyu | |
dc.contributor.author | Conti, Maurizio | |
dc.date.accessioned | 2024-10-02T14:22:24Z | |
dc.date.available | 2024-10-02T14:22:24Z | |
dc.date.issued | 2024 | |
dc.date.openaccess | 0 | |
dc.description.accesstime | w momencie opublikowania | |
dc.description.number | 1 | |
dc.description.version | ostateczna wersja wydawcy | |
dc.description.volume | 11 | |
dc.identifier.articleid | 76 | |
dc.identifier.doi | 10.1186/s40658-024-00678-4 | |
dc.identifier.eissn | 2197-7364 | |
dc.identifier.uri | https://ruj.uj.edu.pl/handle/item/449743 | |
dc.language | eng | |
dc.language.container | eng | |
dc.rights | Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa | |
dc.rights.licence | CC-BY-NC-ND | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl | |
dc.share.type | otwarte czasopismo | |
dc.subject.en | positronium imaging | |
dc.subject.en | positron emission tomography | |
dc.subject.en | molecular imaging | |
dc.subtype | Article | |
dc.title | Positronium lifetime validation measurements using a long-axial field-of-view positron emission tomography scanner | |
dc.title.journal | EJNMMI Physics | |
dc.type | JournalArticle | |
dspace.entity.type | Publication | en |
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