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Predictors of complete remission of type 2 diabetes in patients over 65 years of age - a multicenter study
metabolic surgery
bariatric surgery
older patients
elderly
type 2 diabetes
remission of obesity related diseases
predictors
Introduction
The type 2 diabetes (T2D) improvement rate in the elderly is high after bariatric and metabolic surgery, but not all patients achieve complete remission of disease. There are some predictors for T2D remission after bariatric surgery in patients of different ages, but there are few studies describing these factors in elderly patients. The study aimed to determine predictors for diabetes remission after bariatric surgery among patients over 65 years of age.
Material and methods
A retrospective study analyzed patients over 65 years with T2D who underwent laparoscopic bariatric procedures in European country from 2008 to 2022. Multivariate logistic regression analysis was performed to obtain significant, independent risk factors.
Results
The group consisted of 146 patients divided into two groups: responders (R) and nonresponders (NR). The complete remission of T2D was achieved in 51 (34.9%) patients. There were 95 (65.1%) patients in the NR group with partial remission, improvement, or no changes in T2D. The mean follow-up was 50.0 months. In a multivariate logistic regression analysis, a T2D duration of less than 5 years was found to be a predictor to T2D remission (OR = 5.5, p = 0.002), %EWL significantly corresponded to T2D remission (OR = 1.090, p = 0009).
Conclusion
Bariatric and metabolic surgery appears to be a good option for T2D treatment in elderly patients. A shorter duration of T2D before surgery and higher %EWL after surgery were independent predictors of T2D remission in patients over 65 years of age.
| dc.abstract.en | Introduction The type 2 diabetes (T2D) improvement rate in the elderly is high after bariatric and metabolic surgery, but not all patients achieve complete remission of disease. There are some predictors for T2D remission after bariatric surgery in patients of different ages, but there are few studies describing these factors in elderly patients. The study aimed to determine predictors for diabetes remission after bariatric surgery among patients over 65 years of age. Material and methods A retrospective study analyzed patients over 65 years with T2D who underwent laparoscopic bariatric procedures in European country from 2008 to 2022. Multivariate logistic regression analysis was performed to obtain significant, independent risk factors. Results The group consisted of 146 patients divided into two groups: responders (R) and nonresponders (NR). The complete remission of T2D was achieved in 51 (34.9%) patients. There were 95 (65.1%) patients in the NR group with partial remission, improvement, or no changes in T2D. The mean follow-up was 50.0 months. In a multivariate logistic regression analysis, a T2D duration of less than 5 years was found to be a predictor to T2D remission (OR = 5.5, p = 0.002), %EWL significantly corresponded to T2D remission (OR = 1.090, p = 0009). Conclusion Bariatric and metabolic surgery appears to be a good option for T2D treatment in elderly patients. A shorter duration of T2D before surgery and higher %EWL after surgery were independent predictors of T2D remission in patients over 65 years of age. | |
| dc.affiliation | Wydział Lekarski : Klinika Chirurgii Ogólnej, Onkologicznej i Metabolicznej | pl |
| dc.cm.date | 2023-07-12T07:24:35Z | |
| dc.cm.id | 112596 | pl |
| dc.cm.idOmega | UJCM60fa3649c8344c1db3fc8180ed539c3a | pl |
| dc.contributor.author | Dowgiałło-Gornowicz, Natalia | pl |
| dc.contributor.author | Jaworski, Paweł | pl |
| dc.contributor.author | Walędziak, Maciej | pl |
| dc.contributor.author | Lech, Paweł | pl |
| dc.contributor.author | Kucharska, Alicja | pl |
| dc.contributor.author | Major, Piotr - 141443 | pl |
| dc.date.accession | 2023-07-06 | pl |
| dc.date.accessioned | 2023-07-12T07:24:35Z | |
| dc.date.available | 2023-07-12T07:24:35Z | |
| dc.date.issued | 2023 | pl |
| dc.date.openaccess | 0 | |
| dc.description.accesstime | w momencie opublikowania | |
| dc.description.number | 8 | pl |
| dc.description.physical | 2269-2275 | pl |
| dc.description.version | ostateczna wersja wydawcy | |
| dc.description.volume | 33 | pl |
| dc.identifier.doi | 10.1007/s11695-023-06705-0 | pl |
| dc.identifier.eissn | 1708-0428 | pl |
| dc.identifier.issn | 0960-8923 | pl |
| dc.identifier.uri | https://ruj.uj.edu.pl/xmlui/handle/item/315883 | |
| dc.identifier.weblink | https://doi.org/10.1007/s11695-023-06705-0 | pl |
| dc.language | eng | pl |
| dc.language.container | eng | pl |
| dc.pbn.affiliation | Dziedzina nauk medycznych i nauk o zdrowiu : nauki medyczne | |
| dc.rights | Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa | |
| dc.rights.licence | CC-BY | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/legalcode.pl | |
| dc.share.type | Otwarte czasopismo | |
| dc.source.integrator | false | |
| dc.subject.en | metabolic surgery | |
| dc.subject.en | bariatric surgery | |
| dc.subject.en | older patients | |
| dc.subject.en | elderly | |
| dc.subject.en | type 2 diabetes | |
| dc.subject.en | remission of obesity related diseases | |
| dc.subject.en | predictors | |
| dc.subtype | Article | pl |
| dc.title | Predictors of complete remission of type 2 diabetes in patients over 65 years of age - a multicenter study | pl |
| dc.title.journal | Obesity Surgery | pl |
| dc.type | JournalArticle | pl |
| dspace.entity.type | Publication |
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