Predictors of complete remission of type 2 diabetes in patients over 65 years of age - a multicenter study

2023
journal article
article
10
dc.abstract.enIntroduction The type 2 diabetes (T2D) improvement rate in the elderly is high after bariatric and metabolic surgery, but not all patients achieve complete remission of disease. There are some predictors for T2D remission after bariatric surgery in patients of different ages, but there are few studies describing these factors in elderly patients. The study aimed to determine predictors for diabetes remission after bariatric surgery among patients over 65 years of age. Material and methods A retrospective study analyzed patients over 65 years with T2D who underwent laparoscopic bariatric procedures in European country from 2008 to 2022. Multivariate logistic regression analysis was performed to obtain significant, independent risk factors. Results The group consisted of 146 patients divided into two groups: responders (R) and nonresponders (NR). The complete remission of T2D was achieved in 51 (34.9%) patients. There were 95 (65.1%) patients in the NR group with partial remission, improvement, or no changes in T2D. The mean follow-up was 50.0 months. In a multivariate logistic regression analysis, a T2D duration of less than 5 years was found to be a predictor to T2D remission (OR = 5.5, p = 0.002), %EWL significantly corresponded to T2D remission (OR = 1.090, p = 0009). Conclusion Bariatric and metabolic surgery appears to be a good option for T2D treatment in elderly patients. A shorter duration of T2D before surgery and higher %EWL after surgery were independent predictors of T2D remission in patients over 65 years of age.
dc.affiliationWydział Lekarski : Klinika Chirurgii Ogólnej, Onkologicznej i Metabolicznejpl
dc.cm.date2023-07-12T07:24:35Z
dc.cm.id112596pl
dc.cm.idOmegaUJCM60fa3649c8344c1db3fc8180ed539c3apl
dc.contributor.authorDowgiałło-Gornowicz, Nataliapl
dc.contributor.authorJaworski, Pawełpl
dc.contributor.authorWalędziak, Maciejpl
dc.contributor.authorLech, Pawełpl
dc.contributor.authorKucharska, Alicjapl
dc.contributor.authorMajor, Piotr - 141443 pl
dc.date.accession2023-07-06pl
dc.date.accessioned2023-07-12T07:24:35Z
dc.date.available2023-07-12T07:24:35Z
dc.date.issued2023pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.number8pl
dc.description.physical2269-2275pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume33pl
dc.identifier.doi10.1007/s11695-023-06705-0pl
dc.identifier.eissn1708-0428pl
dc.identifier.issn0960-8923pl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/315883
dc.identifier.weblinkhttps://doi.org/10.1007/s11695-023-06705-0pl
dc.languageengpl
dc.language.containerengpl
dc.pbn.affiliationDziedzina nauk medycznych i nauk o zdrowiu : nauki medyczne
dc.rightsUdzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa
dc.rights.licenceCC-BY
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/legalcode.pl
dc.share.typeOtwarte czasopismo
dc.source.integratorfalse
dc.subject.enmetabolic surgery
dc.subject.enbariatric surgery
dc.subject.enolder patients
dc.subject.enelderly
dc.subject.entype 2 diabetes
dc.subject.enremission of obesity related diseases
dc.subject.enpredictors
dc.subtypeArticlepl
dc.titlePredictors of complete remission of type 2 diabetes in patients over 65 years of age - a multicenter studypl
dc.title.journalObesity Surgerypl
dc.typeJournalArticlepl
dspace.entity.typePublication
dc.abstract.en
Introduction The type 2 diabetes (T2D) improvement rate in the elderly is high after bariatric and metabolic surgery, but not all patients achieve complete remission of disease. There are some predictors for T2D remission after bariatric surgery in patients of different ages, but there are few studies describing these factors in elderly patients. The study aimed to determine predictors for diabetes remission after bariatric surgery among patients over 65 years of age. Material and methods A retrospective study analyzed patients over 65 years with T2D who underwent laparoscopic bariatric procedures in European country from 2008 to 2022. Multivariate logistic regression analysis was performed to obtain significant, independent risk factors. Results The group consisted of 146 patients divided into two groups: responders (R) and nonresponders (NR). The complete remission of T2D was achieved in 51 (34.9%) patients. There were 95 (65.1%) patients in the NR group with partial remission, improvement, or no changes in T2D. The mean follow-up was 50.0 months. In a multivariate logistic regression analysis, a T2D duration of less than 5 years was found to be a predictor to T2D remission (OR = 5.5, p = 0.002), %EWL significantly corresponded to T2D remission (OR = 1.090, p = 0009). Conclusion Bariatric and metabolic surgery appears to be a good option for T2D treatment in elderly patients. A shorter duration of T2D before surgery and higher %EWL after surgery were independent predictors of T2D remission in patients over 65 years of age.
dc.affiliationpl
Wydział Lekarski : Klinika Chirurgii Ogólnej, Onkologicznej i Metabolicznej
dc.cm.date
2023-07-12T07:24:35Z
dc.cm.idpl
112596
dc.cm.idOmegapl
UJCM60fa3649c8344c1db3fc8180ed539c3a
dc.contributor.authorpl
Dowgiałło-Gornowicz, Natalia
dc.contributor.authorpl
Jaworski, Paweł
dc.contributor.authorpl
Walędziak, Maciej
dc.contributor.authorpl
Lech, Paweł
dc.contributor.authorpl
Kucharska, Alicja
dc.contributor.authorpl
Major, Piotr - 141443
dc.date.accessionpl
2023-07-06
dc.date.accessioned
2023-07-12T07:24:35Z
dc.date.available
2023-07-12T07:24:35Z
dc.date.issuedpl
2023
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.numberpl
8
dc.description.physicalpl
2269-2275
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
33
dc.identifier.doipl
10.1007/s11695-023-06705-0
dc.identifier.eissnpl
1708-0428
dc.identifier.issnpl
0960-8923
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/315883
dc.identifier.weblinkpl
https://doi.org/10.1007/s11695-023-06705-0
dc.languagepl
eng
dc.language.containerpl
eng
dc.pbn.affiliation
Dziedzina nauk medycznych i nauk o zdrowiu : nauki medyczne
dc.rights
Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa
dc.rights.licence
CC-BY
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/legalcode.pl
dc.share.type
Otwarte czasopismo
dc.source.integrator
false
dc.subject.en
metabolic surgery
dc.subject.en
bariatric surgery
dc.subject.en
older patients
dc.subject.en
elderly
dc.subject.en
type 2 diabetes
dc.subject.en
remission of obesity related diseases
dc.subject.en
predictors
dc.subtypepl
Article
dc.titlepl
Predictors of complete remission of type 2 diabetes in patients over 65 years of age - a multicenter study
dc.title.journalpl
Obesity Surgery
dc.typepl
JournalArticle
dspace.entity.type
Publication
Affiliations

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