Lipid-based nanocarriers for efficient delivery of lipophilic nutraceuticals

2025
journal article
review article
dc.abstract.enNutraceuticals have received a lot of attention from consumers due to their numerous health benefits and high safety profiles. Demand for efficient delivery of such substances is also due to increased interest in naturally derived products and a healthy lifestyle. In addition to their nutritional values, these substances have anti-inflammatory, antioxidant, and antimicrobial effects, among others, and can prevent and/or treat chronic diseases. Despite various health benefits that nutraceuticals provide, their use in food preparations is commonly limited due to their high sensitivity to external factors, unpleasant odour or taste, low stability, and susceptibility to degradation during in vivo digestion. In addition, many nutraceuticals, including flavonoids, vitamins, fatty acids, curcuminoids, and essential oils have low water solubility, resulting in low bioavailability implying limited health effects. These problems can be solved by encapsulating nutraceuticals in nanocarriers. In particular, lipid-based carriers, including liposomes, nanoemulsions, nanostructured lipid carriers, niosomes, solid lipid nanoparticles, and self-emulsifying drug delivery systems are suitable for incorporating such compounds in the food industry due to their high biocompatibility. In addition, they can increase the bioavailability and stability of encapsulated substances and deliver the substance to a specific place in the body. This review covers characterization of various lipid-based nanocarriers and provides examples of these types of carriers developed in recent years for nutraceutical delivery, along with the benefits they provide.
dc.affiliationSzkoła Doktorska Nauk Ścisłych i Przyrodniczych
dc.affiliationWydział Chemii : Zakład Chemii Fizycznej i Elektrochemii
dc.contributor.authorBednorz, Justyna - 371839
dc.contributor.authorZapotoczny, Szczepan - 132863
dc.date.accession2025-10-21
dc.date.accessioned2025-10-21T09:11:49Z
dc.date.available2025-10-21T09:11:49Z
dc.date.createdat2025-10-20T10:39:24Zen
dc.date.issued2025
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.number173
dc.description.versionostateczna wersja wydawcy
dc.identifier.articleid07
dc.identifier.doi10.34821/eng.biomat.173.2025.07
dc.identifier.issn1429-7248
dc.identifier.projectDRC AI
dc.identifier.urihttps://ruj.uj.edu.pl/handle/item/563335
dc.identifier.weblinkhttp://www.biomaterials.pl/Lipid-based-nanocarriers-for-efficient-delivery-of-lipophilic-nutraceuticals,208362,0,2.html
dc.languageeng
dc.language.containereng
dc.rightsUdzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa
dc.rights.licenceCC-BY
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/legalcode.pl
dc.share.typeotwarte czasopismo
dc.subject.enlipid-based nanocarriers
dc.subject.ennutraceuticals
dc.subject.enbioavailability
dc.subject.enencapsulation
dc.subject.enlipophilic bioactives
dc.subtypeReviewArticle
dc.titleLipid-based nanocarriers for efficient delivery of lipophilic nutraceuticals
dc.title.journalEngineering of Biomaterials / Inżynieria Biomateriałów
dc.typeJournalArticle
dspace.entity.typePublicationen
dc.abstract.en
Nutraceuticals have received a lot of attention from consumers due to their numerous health benefits and high safety profiles. Demand for efficient delivery of such substances is also due to increased interest in naturally derived products and a healthy lifestyle. In addition to their nutritional values, these substances have anti-inflammatory, antioxidant, and antimicrobial effects, among others, and can prevent and/or treat chronic diseases. Despite various health benefits that nutraceuticals provide, their use in food preparations is commonly limited due to their high sensitivity to external factors, unpleasant odour or taste, low stability, and susceptibility to degradation during in vivo digestion. In addition, many nutraceuticals, including flavonoids, vitamins, fatty acids, curcuminoids, and essential oils have low water solubility, resulting in low bioavailability implying limited health effects. These problems can be solved by encapsulating nutraceuticals in nanocarriers. In particular, lipid-based carriers, including liposomes, nanoemulsions, nanostructured lipid carriers, niosomes, solid lipid nanoparticles, and self-emulsifying drug delivery systems are suitable for incorporating such compounds in the food industry due to their high biocompatibility. In addition, they can increase the bioavailability and stability of encapsulated substances and deliver the substance to a specific place in the body. This review covers characterization of various lipid-based nanocarriers and provides examples of these types of carriers developed in recent years for nutraceutical delivery, along with the benefits they provide.
dc.affiliation
Szkoła Doktorska Nauk Ścisłych i Przyrodniczych
dc.affiliation
Wydział Chemii : Zakład Chemii Fizycznej i Elektrochemii
dc.contributor.author
Bednorz, Justyna - 371839
dc.contributor.author
Zapotoczny, Szczepan - 132863
dc.date.accession
2025-10-21
dc.date.accessioned
2025-10-21T09:11:49Z
dc.date.available
2025-10-21T09:11:49Z
dc.date.createdaten
2025-10-20T10:39:24Z
dc.date.issued
2025
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.number
173
dc.description.version
ostateczna wersja wydawcy
dc.identifier.articleid
07
dc.identifier.doi
10.34821/eng.biomat.173.2025.07
dc.identifier.issn
1429-7248
dc.identifier.project
DRC AI
dc.identifier.uri
https://ruj.uj.edu.pl/handle/item/563335
dc.identifier.weblink
http://www.biomaterials.pl/Lipid-based-nanocarriers-for-efficient-delivery-of-lipophilic-nutraceuticals,208362,0,2.html
dc.language
eng
dc.language.container
eng
dc.rights
Udzielam licencji. Uznanie autorstwa 4.0 Międzynarodowa
dc.rights.licence
CC-BY
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.en
lipid-based nanocarriers
dc.subject.en
nutraceuticals
dc.subject.en
bioavailability
dc.subject.en
encapsulation
dc.subject.en
lipophilic bioactives
dc.subtype
ReviewArticle
dc.title
Lipid-based nanocarriers for efficient delivery of lipophilic nutraceuticals
dc.title.journal
Engineering of Biomaterials / Inżynieria Biomateriałów
dc.type
JournalArticle
dspace.entity.typeen
Publication
Affiliations

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