Applicability of attenuation imaging and shear wave elastography in non-invasive assessment of liver steatosis and fibrosis in adult patients

2026
journal article
article
dc.abstract.enPurpose: The study aims to assess whether: 1) shear wave elastography (2D-SWE) and attenuation imaging (ATI) can confirm or dispute ultrasonographic (USG) diagnosis of liver steatosis, 2) there is a correlation between 2D-SWE and ATI results, and 3) which blood tests and liver condition indices are most related to a higher F index among participants. Material and methods: A group of 117 participants (hepatitis B and hepatitis C negative) with B-mode USG-diagnosed fatty liver was examined using ATI and 2D-SWE. Blood tests were performed, and data were analysed for normality, model fitting, and the identification of predictors for a higher F index. The likelihood ratio test assessed variables and their odds ratio in relation to the fibrosis-4 index (FIB-4), followed by interaction analysis with reference patients. Results: ATI and 2D-SWE provided more accurate liver diagnostics than USG. F2-F3 stages correlated with older age, higher glucose, aspartate aminotransferase (AST), FIB-4, De Ritis, AST to platelet ratio index (APRI), and g-glutamyl transpeptidase (GGTP). The model showed that AST was a strong indicator of higher F index. Univariate analysis revealed that higher odds for F2-F3 stages were associated with elevated glucose, FIB-4, De Ritis, ATI, AST, and APRI. Compared to S0, values greater than S1 were linked to a higher F index. Interaction analysis showed that only FIB-4-GGTP was significant, with higher GGTP reducing the impact of FIB-4. Conclusions: ATI and 2D-SWE may complement USG in assessing liver condition. Key predictors for a higher F index include S index, AST, glucose, De Ritis, and FIB-4, with APRI being moderately relevant.
dc.contributor.authorPozowski, Patryk
dc.contributor.authorBilski, Mateusz
dc.contributor.authorLewandowski, Łukasz
dc.contributor.authorZaleska-Dorobisz, Urszula
dc.date.accessioned2026-08-17T07:05:19Z
dc.date.available2026-08-17T07:05:19Z
dc.date.createdat2026-08-17T07:05:19Zen
dc.date.issued2026
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. e269-e270
dc.description.number1
dc.description.physicale255-e279
dc.description.versionostateczna wersja wydawcy
dc.description.volume91
dc.identifier.doi10.5114/pjr/215747
dc.identifier.issn1733-134X
dc.identifier.projectDRC AI
dc.identifier.urihttps://ruj.uj.edu.pl/handle/item/580831
dc.languageeng
dc.language.containereng
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.typeotwarte czasopismo
dc.source.integratorfalse
dc.subject.enattenuation imaging
dc.subject.ennon-alcoholic fatty liver disease
dc.subject.enshear wave elastography
dc.subject.enultrasonography
dc.subtypeArticle
dc.titleApplicability of attenuation imaging and shear wave elastography in non-invasive assessment of liver steatosis and fibrosis in adult patients
dc.title.journalPolish Journal of Radiology
dc.typeJournalArticle
dspace.entity.typePublicationen
dc.abstract.en
Purpose: The study aims to assess whether: 1) shear wave elastography (2D-SWE) and attenuation imaging (ATI) can confirm or dispute ultrasonographic (USG) diagnosis of liver steatosis, 2) there is a correlation between 2D-SWE and ATI results, and 3) which blood tests and liver condition indices are most related to a higher F index among participants. Material and methods: A group of 117 participants (hepatitis B and hepatitis C negative) with B-mode USG-diagnosed fatty liver was examined using ATI and 2D-SWE. Blood tests were performed, and data were analysed for normality, model fitting, and the identification of predictors for a higher F index. The likelihood ratio test assessed variables and their odds ratio in relation to the fibrosis-4 index (FIB-4), followed by interaction analysis with reference patients. Results: ATI and 2D-SWE provided more accurate liver diagnostics than USG. F2-F3 stages correlated with older age, higher glucose, aspartate aminotransferase (AST), FIB-4, De Ritis, AST to platelet ratio index (APRI), and g-glutamyl transpeptidase (GGTP). The model showed that AST was a strong indicator of higher F index. Univariate analysis revealed that higher odds for F2-F3 stages were associated with elevated glucose, FIB-4, De Ritis, ATI, AST, and APRI. Compared to S0, values greater than S1 were linked to a higher F index. Interaction analysis showed that only FIB-4-GGTP was significant, with higher GGTP reducing the impact of FIB-4. Conclusions: ATI and 2D-SWE may complement USG in assessing liver condition. Key predictors for a higher F index include S index, AST, glucose, De Ritis, and FIB-4, with APRI being moderately relevant.
dc.contributor.author
Pozowski, Patryk
dc.contributor.author
Bilski, Mateusz
dc.contributor.author
Lewandowski, Łukasz
dc.contributor.author
Zaleska-Dorobisz, Urszula
dc.date.accessioned
2026-08-17T07:05:19Z
dc.date.available
2026-08-17T07:05:19Z
dc.date.createdaten
2026-08-17T07:05:19Z
dc.date.issued
2026
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additional
Bibliogr. s. e269-e270
dc.description.number
1
dc.description.physical
e255-e279
dc.description.version
ostateczna wersja wydawcy
dc.description.volume
91
dc.identifier.doi
10.5114/pjr/215747
dc.identifier.issn
1733-134X
dc.identifier.project
DRC AI
dc.identifier.uri
https://ruj.uj.edu.pl/handle/item/580831
dc.language
eng
dc.language.container
eng
dc.rights
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.source.integrator
false
dc.subject.en
attenuation imaging
dc.subject.en
non-alcoholic fatty liver disease
dc.subject.en
shear wave elastography
dc.subject.en
ultrasonography
dc.subtype
Article
dc.title
Applicability of attenuation imaging and shear wave elastography in non-invasive assessment of liver steatosis and fibrosis in adult patients
dc.title.journal
Polish Journal of Radiology
dc.type
JournalArticle
dspace.entity.typeen
Publication
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