Following the recent attempts to rehabilitate the reputation of Ctesias and the information given in his works, this paper proposes to understand certain of the seemingly fanciful details that were associated with the physician and his writings. It tries to shed some light on several uncertainties connected with Ctesias (i.e., his sojourn in Persia) and the Persica (i.e., date, original style and sources of imagery). It argues that the pedestrian lists included in the work might have been later interpolations and that the minor works circulating under Ctesias’ name might have been either sections of the Persica that were taken out to be presented as stand-alone volumes or else falsely attributed to him. The paper addresses the Indica and puts forward several possibilities concerning its relation with the Persica. The infl uence of Ctesias on the author Deinon is examined, and in the appendix the impact of the Persica on Xenophon’s Anabasis is analyzed.