Apparent diffusion coefficient of different areas of brain in foetuses with intrauterine growth restriction

2020
journal article
article
7
cris.lastimport.wos2024-04-09T20:21:25Z
dc.abstract.enIntroduction: This study aimed to compare the apparent diffusion coefficient (ADC) values of different brain areas between two groups of intrauterine growth restricted (IUGR) foetuses and control cases. Material and methods: A total of 38 foetuses with IUGR and 18 normal control foetuses with similar gestational age were compared using a 3T magnetic resonance scanner. IUGR cases included 23 foetuses with clinical severity signs (group A) and 15 foetuses without clinical severity signs (group B). ADC values were measured in different brain regions and compared among groups. Foetuses with structural brain abnormalities were excluded from the study. Results: All foetuses had normal foetal structural brain anatomy. Head circumference (HC) < 5% was more common in IUGR group A compared to IUGR group B (56.5% vs. 13.3%, p < 0.0001). In comparison to the normal group, the ADC values in IUGR foetuses were significantly lower in cerebellar hemispheres (CH) (1.239 vs. 1.280.5 × 10-3 mm2/s, p = 0.045), thalami (1.205 vs. 1.285 × 10–3 mm2/s, p = 0.031) and caudate nucleus (CN) (1.319 vs. 1.394 × 10-3 mm2/s, p = 0.04). However, there were no significant differences in ADC values between IUGR subtypes. Among all brain regions, pons had the lowest ADC values. Conclusions: ADC values of thalami, CN, and CH were significantly lower in IUGR than control foetuses, while there was no significant difference among IUGR groups. Further studies are needed to evaluate the prognostic value of ADC changes in IUGR foetuses.pl
dc.contributor.authorMoradi, Behnazpl
dc.contributor.authorNezhad, Zohreh Alibeigipl
dc.contributor.authorSeyed Saadat, Nazaninpl
dc.contributor.authorShirazi, Mahboobehpl
dc.contributor.authorBorhani, Alipl
dc.contributor.authorKazemi, Mohammad Alipl
dc.date.accessioned2020-07-08T11:54:12Z
dc.date.available2020-07-08T11:54:12Z
dc.date.issued2020pl
dc.date.openaccess0
dc.description.accesstimew momencie opublikowania
dc.description.additionalBibliogr. s. e307-e308pl
dc.description.physicale301-e308pl
dc.description.versionostateczna wersja wydawcy
dc.description.volume85pl
dc.identifier.doi10.5114/pjr.2020.96950pl
dc.identifier.eissn1899-0967pl
dc.identifier.issn1733-134Xpl
dc.identifier.urihttps://ruj.uj.edu.pl/xmlui/handle/item/165474
dc.languageengpl
dc.language.containerengpl
dc.rightsUdzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa*
dc.rights.licenceCC-BY-NC-ND
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl*
dc.share.typeotwarte czasopismo
dc.subject.enapparent diffusion coefficientpl
dc.subject.enfoetuspl
dc.subject.endiffusion-weighted imagingpl
dc.subject.enhypoxiapl
dc.subject.engrowth restrictionpl
dc.subtypeArticlepl
dc.titleApparent diffusion coefficient of different areas of brain in foetuses with intrauterine growth restrictionpl
dc.title.journalPolish Journal of Radiologypl
dc.typeJournalArticlepl
dspace.entity.typePublication
cris.lastimport.wos
2024-04-09T20:21:25Z
dc.abstract.enpl
Introduction: This study aimed to compare the apparent diffusion coefficient (ADC) values of different brain areas between two groups of intrauterine growth restricted (IUGR) foetuses and control cases. Material and methods: A total of 38 foetuses with IUGR and 18 normal control foetuses with similar gestational age were compared using a 3T magnetic resonance scanner. IUGR cases included 23 foetuses with clinical severity signs (group A) and 15 foetuses without clinical severity signs (group B). ADC values were measured in different brain regions and compared among groups. Foetuses with structural brain abnormalities were excluded from the study. Results: All foetuses had normal foetal structural brain anatomy. Head circumference (HC) < 5% was more common in IUGR group A compared to IUGR group B (56.5% vs. 13.3%, p < 0.0001). In comparison to the normal group, the ADC values in IUGR foetuses were significantly lower in cerebellar hemispheres (CH) (1.239 vs. 1.280.5 × 10-3 mm2/s, p = 0.045), thalami (1.205 vs. 1.285 × 10–3 mm2/s, p = 0.031) and caudate nucleus (CN) (1.319 vs. 1.394 × 10-3 mm2/s, p = 0.04). However, there were no significant differences in ADC values between IUGR subtypes. Among all brain regions, pons had the lowest ADC values. Conclusions: ADC values of thalami, CN, and CH were significantly lower in IUGR than control foetuses, while there was no significant difference among IUGR groups. Further studies are needed to evaluate the prognostic value of ADC changes in IUGR foetuses.
dc.contributor.authorpl
Moradi, Behnaz
dc.contributor.authorpl
Nezhad, Zohreh Alibeigi
dc.contributor.authorpl
Seyed Saadat, Nazanin
dc.contributor.authorpl
Shirazi, Mahboobeh
dc.contributor.authorpl
Borhani, Ali
dc.contributor.authorpl
Kazemi, Mohammad Ali
dc.date.accessioned
2020-07-08T11:54:12Z
dc.date.available
2020-07-08T11:54:12Z
dc.date.issuedpl
2020
dc.date.openaccess
0
dc.description.accesstime
w momencie opublikowania
dc.description.additionalpl
Bibliogr. s. e307-e308
dc.description.physicalpl
e301-e308
dc.description.version
ostateczna wersja wydawcy
dc.description.volumepl
85
dc.identifier.doipl
10.5114/pjr.2020.96950
dc.identifier.eissnpl
1899-0967
dc.identifier.issnpl
1733-134X
dc.identifier.uri
https://ruj.uj.edu.pl/xmlui/handle/item/165474
dc.languagepl
eng
dc.language.containerpl
eng
dc.rights*
Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
dc.rights.licence
CC-BY-NC-ND
dc.rights.uri*
http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode.pl
dc.share.type
otwarte czasopismo
dc.subject.enpl
apparent diffusion coefficient
dc.subject.enpl
foetus
dc.subject.enpl
diffusion-weighted imaging
dc.subject.enpl
hypoxia
dc.subject.enpl
growth restriction
dc.subtypepl
Article
dc.titlepl
Apparent diffusion coefficient of different areas of brain in foetuses with intrauterine growth restriction
dc.title.journalpl
Polish Journal of Radiology
dc.typepl
JournalArticle
dspace.entity.type
Publication
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