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Intracellular redox potential is a highly regulated cellular characteristic and is critically involved in main-
taining cellular health and function. The dysregulation of redox potential can result in the initiation and
progression of numerous diseases. Redox potential is determined by the balance of oxidants and reduc-
tants in the cell and also by pH. For this reason a technique for quantitative measurement of intracellular
redox potential and pH is highly desirable. In this paper we demonstrate how surface enhanced Raman
scattering (SERS) nanosensors can be used for multiplexed measurement of both pH and redox potential
in live single cells.
affiliation:
Wydział Chemii : Zakład Fizyki Chemicznej, Pion Rektora : Jagiellońskie Centrum Rozwoju Leków