Jagiellonian University Repository
Preparation and characterization of chitosan : silver nanocomposite films and their antibacterial activity against Staphylococcus aureus
Communities & Collections
pcg.skipToMenu
Preparation and characterization of chitosan : silver nanocomposite films and their antibacterial activity against Staphylococcus aureus
Bibliographic description
| title: | Preparation and characterization of chitosan : silver nanocomposite films and their antibacterial activity against Staphylococcus aureus |
| author: | Regiel-Futyra Anna  , Irusta Silvia, Kyzioł Agnieszka , Arruebo Manuel, Santamaria Jesus |
| journal title: | Nanotechnology |
| volume: | 24 |
| issue: | 1 |
| date of publication : | 2013 |
| article ID: | 015101 |
| ISSN: |
0957-4484 |
| eISSN: |
1361-6528 |
| DOI: | |
| notes: | Na publikacji autorka podpisana: Anna Regiel. Anna Regiel - Faculty of Chemistry, Jagiellonian University |
| language: | English |
| journal language: | English |
| abstract in English: | In this work different variables have been analyzed in order to optimize the bactericidal properties of chitosan films loaded with silver nanoparticles. The goal was to achieve complete elimination of antibiotic resistant and biofilm forming strains of Staphylococcus aureus after short contact times. The films were produced by solution casting using chitosan as both a stabilizing and reducing agent for the in situ synthesis of embedded silver nanoparticles. We have applied an innovative approach: the influence of the chitosan molecular weight and its deacetylation degree (DD) were analyzed together with the influence of the bacterial concentration and contact time. The best results were obtained with high DD chitosan where a fast reduction was favored; leading to smaller nanoparticles (nucleation is promoted), and a sufficiently high polymer viscosity prevented the resulting nanoparticles from undesired agglomeration. In addition, for the first time, potential detachment of the silver nanoparticles from the films was evaluated and neglected, demonstrating that uncontrolled release of silver nanoparticles from the chitosan films is prevented. The influence of the ionic silver released from the films, silver loading, nanoparticle sizes, contact, and initial number of bacteria was also analyzed to elucidate the mechanism responsible for the strong bactericidal action observed. |
| affiliation: | Wydział Chemii : Zakład Chemii Nieorganicznej |
| type: | journal article |
| subtype: | academic paper |
Files in this item
| Files | Size | Format | View |
|---|---|---|---|
|
There are no files associated with this item. |
|||
This item appears in the following Collection(s)
Projekt „Repozytorium otwartego dostępu do dorobku naukowego i dydaktycznego UJ” współfinansowany w ramach poddziałania 2.3.1 „Cyfrowe udostępnianie zasobów nauki” Programu Operacyjnego Polska Cyfrowa z Europejskiego Funduszu Rozwoju Regionalnego i budżetu państwa na podstawie umowy o dofinansowanie nr POPC.02.03.01-00-0030/17-00
