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Local response of esophageal carcinoma to neoadjuvant chemotherapy in CT examination according to WHO and RECIST criteria

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Local response of esophageal carcinoma to neoadjuvant chemotherapy in CT examination according to WHO and RECIST criteria

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dc.contributor.author Pasławski, Marek pl
dc.contributor.author Kołtyś, Witold pl
dc.contributor.author Złomaniec, Janusz pl
dc.date.accessioned 2019-08-16T06:48:14Z
dc.date.available 2019-08-16T06:48:14Z
dc.date.issued 2006 pl
dc.identifier.issn 1733-134X pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/80811
dc.language pol pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/pl/legalcode *
dc.title Local response of esophageal carcinoma to neoadjuvant chemotherapy in CT examination according to WHO and RECIST criteria pl
dc.title.alternative Ocena stopnia miejscowej odpowiedzi raka przełyku na chemioterapię przedoperacyjną w tomografii komputerowej : kryteria WHO i RECIST pl
dc.type JournalArticle pl
dc.description.physical 7-10 pl
dc.description.additional Bibliogr. s. 10 pl
dc.identifier.weblink http://archiwum.inforadiologia.pl/download/index/idArt/456358.html pl
dc.abstract.en Background: The aim of the study was to compare the WHO and RECIST criteria of esophageal carcinoma chemotherapy response. Material/Methods: Neoadjuvant chemotherapy was applied in a group of 52 patients with esophageal carcinoma. CT examination of the esophagus was performed in all of them before and after the appropriate course of therapy and chemotherapy response was assessed according to both WHO and RECIST criteria. The results were analyzed using the statistical software Statistica PL 5.0. Results: Complete response was found in 8 patients according to both WHO and RECIST criteria. Partial response was found in 8 patients according to WHO criteria and in 19 patients according to RECIST criteria. Stabile disease was found in 32 patients according to WHO criteria and in 20 patients according to RECIST criteria. Progression of the disease was found in 4 patients according to WHO criteria and in 5 according to RECIST. Eleven patients classified as having stabilization of the disease according to WHO criteria were classified as having partial response according to RECIST criteria. One patient classified as having stabilization of the disease according to WHO criteria was classified as having progression according to RECIST criteria. The difference was statistically significant (p=0.012). Conclusions: There are statistically significant differences between the WHO and RECIST classifications of chemotherapy response in esophageal carcinoma. The classification system must be determined when chemotherapy response is assessed. Determining which one, WHO or RECIST, is more suitable for assessing chemotherapy response of esophageal carcinoma requires additional study, including an evaluation of the survival rate in responders according to both systems. pl
dc.subject.en esophageal carcinoma pl
dc.subject.en neoadjuvant chemotherapy pl
dc.subject.en WHO criteria pl
dc.subject.en RECIST criteria pl
dc.description.volume 71 pl
dc.description.number 3 pl
dc.identifier.eissn 1899-0967 pl
dc.title.journal Polish Journal of Radiology pl
dc.language.container pol pl
dc.date.accession 2019-08-16 pl
dc.subtype Article pl
dc.identifier.articleid 456358 pl
dc.rights.original CC-BY-NC-ND; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa