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Detection of asymptomatic brain involvement in systemic sclerosis

Detection of asymptomatic brain involvement in ...

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dc.contributor.author Walecka, Irena pl
dc.contributor.author Sicinska, Justyna pl
dc.contributor.author Szymanska, Elzbieta pl
dc.contributor.author Slowinska, Monika pl
dc.contributor.author Cwikla, Jaroslaw pl
dc.contributor.author Olszewska, Malgorzata pl
dc.contributor.author Pniewski, Jaroslaw pl
dc.contributor.author Walecki, Jerzy pl
dc.contributor.author Rudnicka, Lidia pl
dc.date.accessioned 2019-05-20T06:09:41Z
dc.date.available 2019-05-20T06:09:41Z
dc.date.issued 2008 pl
dc.identifier.issn 1733-134X pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/75142
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/pl/legalcode *
dc.title Detection of asymptomatic brain involvement in systemic sclerosis pl
dc.type JournalArticle pl
dc.description.physical 12-15 pl
dc.description.additional Bibliogr. s. 14-15 pl
dc.identifier.weblink http://archiwum.inforadiologia.pl/download/index/idArt/878362.html pl
dc.abstract.en Background: Systemic sclerosis is a chronic connective tissue disease, characterized by vascular changes, accompanied by fibrosis of the skin and internal organs. Neuropsychiatric symptoms are considered rare in these patients. Objectives The aim of the study was to evaluate frequency of morphological brain abnormalities in those patients with systemic sclerosis, who demonstrate no clinical symptoms of central nervous system involvement. Material/Methods: 24 patients with systemic sclerosis, who had no neurological or psychiatric abnormalities were included into the study. In all patients brain magnetic resonance imaging was performed. Fluidattenuated inversion-recovery and fast spin-echo magnetic resonance imaging sequences were used. Results: In 37% (9/24) of these patients brain magnetic resonance images revealed abnormalities. These included: cortical and subcortical atrophy (4/24), single focal lesions (5/24) or diffuse lesions (2/24). In 3 patients simultaneous presence of more then one of these abnormalities was detected. Brain computer tomography revealed abnormalities in 2/24 (8%) of patients. Conclusions: Our results indicate, that the central nervous system may be involved in systemic sclerosis despite lack of neuropsychiatric symptoms. Brain magnetic resonance imaging allows early detection of these abnormalities. We suggest to perform brain magnetic resonance in all patients of systemic sclerosis before introducing treatment. pl
dc.subject.en brain pl
dc.subject.en magnetic resonance imaging pl
dc.subject.en scleroderma pl
dc.subject.en systemic sclerosis pl
dc.description.volume 73 pl
dc.description.number 4 pl
dc.identifier.eissn 1899-0967 pl
dc.title.journal Polish Journal of Radiology pl
dc.language.container eng pl
dc.date.accession 2019-05-20 pl
dc.subtype Article pl
dc.identifier.articleid 878362 pl
dc.rights.original CC-BY-NC-ND; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa