Impact of vanadium complexes treatment on the oxidative stress factors in Wistar rats plasma
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dc.type
JournalArticle
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dc.description.additional
Bibliogr. 206316-7 - 206316-8.
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dc.identifier.weblink
https://www.hindawi.com/journals/bca/2011/206316/
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dc.abstract.en
The aim of this study was to investigate the clinical efficacy of vanadium complexes on triglycerides (TG), total cholesterol
(Chol), uric acid (UA), urea (U), and antioxidant parameters: nonenzymatic (FRAP-ferric reducing ability of plasma, and
reduced glutathione-GSH) and enzymatic (glutathione peroxidase-GPx, catalase-CAT, and GPx/CAT ratio) activity in the
plasma of healthy male Wistar rats. Three vanadium complexes: [VO(bpy)2]SO4·2H2O, [VO(4,4
Me2bpy)2]SO4·2H2O, and
Na[VO(O2)2(bpy)]·8H2O are administered by gavage during 5 weeks in two different diets such as control (C) and high fatty (F)
diets. Changes of biochemical and antioxidants parameters are measured in plasma. All three vanadium complexes statistically
decrease the body mass growth in comparison to the control and fatty diet. In plasma GSH was statistically increased in all
vanadium complexes-treated rats from control and fatty group in comparison to only control group. Calculated GPX/CAT ratio
was the highest in the control group in comparison to others.
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dc.description.volume
2011
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dc.identifier.doi
10.1155/2011/206316
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dc.identifier.eissn
1687-479X
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dc.title.journal
Bioinorganic Chemistry and Applications
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dc.language.container
eng
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dc.date.accession
2019-03-27
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dc.affiliation
Wydział Chemii : Zakład Chemii Nieorganicznej
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dc.affiliation
Wydział Farmaceutyczny : Zakład Radioligandów
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dc.affiliation
Wydział Farmaceutyczny : Zakład Bromatologii
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dc.affiliation
Wydział Farmaceutyczny : Zakład Chemii Bioorganicznej
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dc.subtype
Article
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dc.identifier.articleid
206316
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dc.rights.original
CC-BY; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0