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Prognostic value of duration of untreated psychosis in long-term outcome of schizophrenia

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Prognostic value of duration of untreated psychosis in long-term outcome of schizophrenia

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dc.contributor.author Cechnicki, Andrzej [SAP20000367] pl
dc.contributor.author Hanuszkiewicz, Igor pl
dc.contributor.author Polczyk, Romuald [SAP11016148] pl
dc.contributor.author Bielańska, Anna pl
dc.date.accessioned 2018-12-28T12:35:13Z
dc.date.available 2018-12-28T12:35:13Z
dc.date.issued 2011 pl
dc.identifier.issn 1234-1010 pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/64602
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/pl/legalcode *
dc.title Prognostic value of duration of untreated psychosis in long-term outcome of schizophrenia pl
dc.type JournalArticle pl
dc.description.physical 277-283 pl
dc.description.additional Bibliogr s. 283 pl
dc.identifier.weblink https://www.medscimonit.com/download/index/idArt/881768 pl
dc.abstract.en The goal of this prognostic study was to investigate whether the duration of untreated psychosis (DUP) may have a prognostic value with regard to the further course of the illness. Material/Methods: Fifty-eight patients (77% of the original study group) diagnosed with DSM III schizophrenia and later re-diagnosed with DSM IV T-R were assessed at 4 time points. Number of relapses, average time of inpatient treatment, number of inpatient readmissions, and severity of psychopathological symptoms were assessed at 1-, 3-, 7- and 12-year follow-ups. DUP information was obtained by clinical interview with patients and their families. The severity of symptoms was assessed using BPRS-SA, UCLA version. Results: Increases in the number of relapses at follow-ups were more prominent in the group with a longer DUP (p<0.001). Decreases in the results of BPRS (symptom improvement) were more prominent in patients with a shorter DUP. The latter had significantly lower results than patients with a long DUP at each assessment except the index hospitalization (p equalled, respectively: 0.449; 0.002; 0.012; 0.034 and 0.014). Decreases in positive symptoms were greater in patients with a short DUP – significant at all except the 7-year follow-up (p equalled respectively: 0.230; <0.001; 0.011; 0.214; <0.001). Conclusions: 1) A positive correlation was found between DUP and the dynamics of general and positive symptoms and the number of relapses. 2) There was no significant relationship between DUP and the dynamics of negative symptoms, whereas the relationship between the time and number of re-hospitalizations was marginally significant. pl
dc.subject.pl schizofrenia pl
dc.subject.pl przebieg choroby pl
dc.subject.pl czas trwania nieleczonej psychozy pl
dc.subject.en schizophrenia pl
dc.subject.en course of illness pl
dc.subject.en duration of untreated psychosis pl
dc.description.volume 17 pl
dc.description.number 5 pl
dc.identifier.doi 10.12659/MSM.881768 pl
dc.identifier.eissn 1643-3750 pl
dc.title.journal Medical Science Monitor pl
dc.language.container eng pl
dc.date.accession 2018-10-18 pl
dc.affiliation Wydział Filozoficzny : Instytut Psychologii pl
dc.affiliation Wydział Lekarski pl
dc.subtype Article pl
dc.rights.original CC-BY-NC-ND; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl
.pointsMNiSW [2011 A]: 20


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa