Jagiellonian University Repository
Prognostic value of duration of untreated psychosis in long-term outcome of schizophrenia
Communities & Collections
pcg.skipToMenu
Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
Prognostic value of duration of untreated psychosis in long-term outcome of schizophrenia
Bibliographic description
| title: | Prognostic value of duration of untreated psychosis in long-term outcome of schizophrenia |
| author: | Cechnicki Andrzej  , Hanuszkiewicz Igor, Polczyk Romuald , Bielańska Anna |
| journal title: | Medical Science Monitor |
| volume: | 17 |
| issue: | 5 |
| date of publication : | 2011 |
| pages: | 277-283 |
| ISSN: |
1234-1010 |
| eISSN: |
1643-3750 |
| DOI: | |
| URL: | |
| date accessed: |
2018-10-18 |
| notes: | Bibliogr s. 283 |
| language: | English |
| journal language: | English |
| abstract in English: | The goal of this prognostic study was to investigate whether the duration of untreated psychosis (DUP) may have a prognostic value with regard to the further course of the illness. Material/Methods: Fifty-eight patients (77% of the original study group) diagnosed with DSM III schizophrenia and later re-diagnosed with DSM IV T-R were assessed at 4 time points. Number of relapses, average time of inpatient treatment, number of inpatient readmissions, and severity of psychopathological symptoms were assessed at 1-, 3-, 7- and 12-year follow-ups. DUP information was obtained by clinical interview with patients and their families. The severity of symptoms was assessed using BPRS-SA, UCLA version. Results: Increases in the number of relapses at follow-ups were more prominent in the group with a longer DUP (p<0.001). Decreases in the results of BPRS (symptom improvement) were more prominent in patients with a shorter DUP. The latter had significantly lower results than patients with a long DUP at each assessment except the index hospitalization (p equalled, respectively: 0.449; 0.002; 0.012; 0.034 and 0.014). Decreases in positive symptoms were greater in patients with a short DUP – significant at all except the 7-year follow-up (p equalled respectively: 0.230; <0.001; 0.011; 0.214; <0.001). Conclusions: 1) A positive correlation was found between DUP and the dynamics of general and positive symptoms and the number of relapses. 2) There was no significant relationship between DUP and the dynamics of negative symptoms, whereas the relationship between the time and number of re-hospitalizations was marginally significant. |
| keywords in Polish: | schizofrenia, przebieg choroby, czas trwania nieleczonej psychozy |
| keywords in English: | schizophrenia, course of illness, duration of untreated psychosis |
| affiliation: | Wydział Filozoficzny : Instytut Psychologii, Wydział Lekarski |
| type: | journal article |
| subtype: | academic paper |
Files in this item
This item appears in the following Collection(s)
Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa
Projekt „Repozytorium otwartego dostępu do dorobku naukowego i dydaktycznego UJ” współfinansowany w ramach poddziałania 2.3.1 „Cyfrowe udostępnianie zasobów nauki” Programu Operacyjnego Polska Cyfrowa z Europejskiego Funduszu Rozwoju Regionalnego i budżetu państwa na podstawie umowy o dofinansowanie nr POPC.02.03.01-00-0030/17-00
