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Application of own computer program for assessment of brain-fluid index in the medial temporal lobe portions in patients with drug-resistant temporal lobe epilepsy

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Application of own computer program for assessment of brain-fluid index in the medial temporal lobe portions in patients with drug-resistant temporal lobe epilepsy

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dc.contributor.author Bogusławska, Romana pl
dc.contributor.author Rysz, A. pl
dc.contributor.author Rakowicz, M. pl
dc.contributor.author Poniatowska, R. pl
dc.contributor.author Krawczyk, R. pl
dc.contributor.author Makulec, A. pl
dc.contributor.author Skrobowska, E. pl
dc.contributor.author Koszewski, W. pl
dc.contributor.author Walecki, J. pl
dc.contributor.author Ryterski, J. pl
dc.date.accessioned 2018-12-12T10:26:14Z
dc.date.available 2018-12-12T10:26:14Z
dc.date.issued 2009 pl
dc.identifier.issn 1733-134X pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/63533
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/pl/legalcode *
dc.title Application of own computer program for assessment of brain-fluid index in the medial temporal lobe portions in patients with drug-resistant temporal lobe epilepsy pl
dc.title.alternative Zastosowanie własnego programu komputerowego do oceny współczynnika płynowo-mózgowego przyśrodkowych części płatów skroniowych u chorych na lekooporną padaczkę skroniową pl
dc.type JournalArticle pl
dc.description.physical 24-29 pl
dc.description.additional Bibliogr. s. 29 pl
dc.identifier.weblink http://archiwum.polradiol.com/abstract/index/idArt/878401 pl
dc.abstract.en Background: Epilepsy resistant to pharmacological treatment still remains one of the main problems in contemporary epileptology. The problem most frequently concerns patients with focal epilepsy, with the seizure focus possible to localize. In case of drug-resistant epilepsy, both morphological imaging methods (MR) and manual measurementa or volumetry are used. Also functional studies, such as MRS (magnetic resonance spectroscopy), fMRI (functional magnetic resonance), SPECT (single photon emission tomography) and PET (positron emission tomography) are performed. Material/Methods: The study presents application of own computer program based on the method of segmentation of the cerebrospinal fluid (CSF) and the brain tissue. The program calculates automatically the brain-fluin index in the hippocampal region. The material comprises the brain-fluin index results calculated with the presented program in comparison with the method of manual delineation in a group of 50 patients with drug-resistant temporal lobe epilepsy. The program is easy to use, it reads the MR data recorded in DICOM installed on a PC. Results: The brain-fluin index result (expressed as a decimal fraction) is calculated on the basis of 4 consecutive layers examined by MR (evaluating hippocampal structures) performed using SE sequence, and T2-weighted imaging in the frontal plane perpendicular to the long axis of the temporal lobes. The results obtained in epilepsy patients were compared with 24 control subjects. Conclusions: Detailed analysis of the obtained data allowed to conclude that precise hippocampal volume assessment can be obtained by combination of both methods, i.e. manual delineation and automatic calculation of brain-fluin index taking into consideration the total volume of cerebral structures. pl
dc.subject.en temporal lobe epilepsy pl
dc.subject.en manual measurement methods pl
dc.subject.en volumetric methods pl
dc.subject.en MRS (magnetic resonance spectroscopy) pl
dc.description.volume 74 pl
dc.description.number 3 pl
dc.identifier.eissn 1899-0967 pl
dc.title.journal Polish Journal of Radiology pl
dc.language.container eng pl
dc.date.accession 2018-12-12 pl
dc.subtype Article pl
dc.identifier.articleid 878401 pl
dc.rights.original CC-BY-NC-ND; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa