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MR spectroscopy in patients after surgical clipping and endovascular embolisation of intracranial aneurysms

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MR spectroscopy in patients after surgical clipping and endovascular embolisation of intracranial aneurysms

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dc.contributor.author Tarasów, Eugeniusz pl
dc.contributor.author Kochanowicz, Jan pl
dc.contributor.author Brzozowska, Joanna pl
dc.contributor.author Mariak, Zenon pl
dc.contributor.author Walecki, Jerzy pl
dc.date.accessioned 2018-10-12T07:06:26Z
dc.date.available 2018-10-12T07:06:26Z
dc.date.issued 2010 pl
dc.identifier.issn 1733-134X pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/57937
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/pl/legalcode *
dc.title MR spectroscopy in patients after surgical clipping and endovascular embolisation of intracranial aneurysms pl
dc.title.alternative Spektroskopia MR u chorych po klipsowaniu chirurgicznym i wewnątrznaczyniowej embolizacji tętniaków wewnątrzczaszkowych pl
dc.type JournalArticle pl
dc.description.physical 24-29 pl
dc.description.additional Bibliogr. s. 28-29 pl
dc.identifier.weblink http://archiwum.polradiol.com/abstract/index/idArt/881336 pl
dc.abstract.en Background: In MR spectroscopy, we evaluated cerebral metabolic changes in patients 2-4 years after clipping or endovascular therapy of intracranial aneurysms. Material/Metodhs: A prospective study was conducted in 36 patients after SAH, treated surgically (n=23) or by endovascular embolisation (n=13). Control group consisted of 20 healthy volunteers. The clinical evaluation was based on the Glasgow Coma Scale, Hunt and Hess grade, and Glasgow Outcome Scale. MR spectroscopy was performed with 1.5T system with PRESS sequence, at echo time of 35 ms, in frontal lobes unchanged in MR examination. Ratios of N-acetylaspartate (NAA), choline (Cho), myo-inositol (mI) and glutamine/glutamate complex (Glx) to creatine were assessed. Results: Only a slight, statistically insignificant reduction of NAA/Cr and an insignificant increase of mI/Cr were noted; other metabolite ratios were close to the ones in the control group. Similar results were obtained in patients after surgical clipping and after endovascular therapy. Only in patients with aneurysms of anterior communicating artery complex (AcoA), the NAA/Cr ratio showed a significant reduction as compared to that of non-AcoA patients and of the control group. No significant changes of metabolite ratios were found in patients with internal carotid artery (ICA) and middle cerebral artery (MCA) aneurysms, with regard to aneurysm lateralisation. Conclusions: Surgical clipping and endovascular embolisation of ICA, MCA and posterior circulatory aneurysms do not induce changes in metabolite concentration in frontal lobes assessed in MR spectroscopy. In patients with AcoA aneurysms, 2-4 years after obliteration, there were found persistent metabolic changes in unchanged brain tissue of the frontal lobes, corresponding to neuronal damage (dysfunction). pl
dc.subject.en MR spectroscopy pl
dc.subject.en intracranial aneurysms pl
dc.subject.en clipping pl
dc.subject.en embolisation pl
dc.description.volume 75 pl
dc.description.number 4 pl
dc.identifier.eissn 1899-0967 pl
dc.title.journal Polish Journal of Radiology pl
dc.language.container eng pl
dc.date.accession 2018-10-12 pl
dc.subtype Article pl
dc.identifier.articleid 881336 pl
dc.rights.original CC-BY-NC-ND; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa