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Usefulness of corregistration and post-processing of MR and interictal SPECT images for localization of epileptogenic focus in children : preliminary report

Usefulness of corregistration and post-processing ...

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dc.contributor.author Miśko, Jolanta pl
dc.contributor.author Jurkiewicz, Elżbieta pl
dc.contributor.author Bekiesińska-Figatowska, Monika pl
dc.contributor.author Kamińska, Anna pl
dc.contributor.author Bachański, Zbigniew pl
dc.contributor.author Chełstowska, Sylwia pl
dc.contributor.author Walecki, Jerzy pl
dc.date.accessioned 2018-09-18T07:32:51Z
dc.date.available 2018-09-18T07:32:51Z
dc.date.issued 2011 pl
dc.identifier.issn 1733-134X pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/57024
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/pl/legalcode *
dc.title Usefulness of corregistration and post-processing of MR and interictal SPECT images for localization of epileptogenic focus in children : preliminary report pl
dc.type JournalArticle pl
dc.description.physical 7-14 pl
dc.description.additional Bibliogr. s. 14 pl
dc.identifier.weblink http://archiwum.polradiol.com/abstract/index/idArt/882138 pl
dc.abstract.en Background: Children with focal epilepsy unresponsive to anticonvulsant therapy may become surgical candidates. Inter-ictal SPECT (SPECT-IN) studies demonstrate an area of hypoperfusion within the seizure focus in up to 50% of patients. The goal of this study was to evaluate the usefulness of corregistration of MR and SPECT-IN images for localization of the epileptogenic focus. Material/Methods: Brain MRI and SPECT-IN were performed in 20 children (mean age 9.5). We found multifocal (3-6 perfusion deficits in 10 patients) or diffuse perfusion deficits (lobar) in all patients. In fused MR and SPECT images we evaluated average activity in volumes-of-interest (VOIs) outlined in each gray matter region with deficits. Average VOI activity below average total brain activity with at least 15% difference to the mirror VOI in the brain cortex on the opposite side of was considered as "true" perfusion deficit (TPD). Results: In all children from our group, MRI and SPECT-IN image fusion and evaluation of TPD allowed to verify most of multifocal or diffuse deficits: in each of 12 patients we found 1 TPD, in each of 6 patients 2 TPD and in each of 2 patients 3 TPD. In 8 patients with 2 or 3 TPD we used scalp EEG or ictal SPECT for identification of one probable location of epileptogenic focus. Conclusions: In children with refractory focal epilepsy, image fusion of MRI and SPECT-IN with evaluation of TPD has potential clinical utility in localization of epileptogenic focus. pl
dc.subject.en epilepsy in infants pl
dc.subject.en magnetic resonance imaging (MRI) pl
dc.subject.en single photon emission computed tomography (SPECT) pl
dc.description.volume 76 pl
dc.description.number 4 pl
dc.identifier.eissn 1899-0967 pl
dc.title.journal Polish Journal of Radiology pl
dc.language.container eng pl
dc.date.accession 2018-09-18 pl
dc.subtype Article pl
dc.identifier.articleid 882138 pl
dc.rights.original CC-BY-NC-ND; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa