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Computed tomography perfusion examination is helpful in evaluating the extent of oropharyngeal and oral cavity cancer

Computed tomography perfusion examination is helpful ...

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dc.contributor.author Trojanowska, Agnieszka pl
dc.contributor.author Grzycka-Kowalczyk, Luiza pl
dc.contributor.author Trojanowski, Piotr pl
dc.contributor.author Klatka, Janusz pl
dc.contributor.author Drop, Andrzej pl
dc.date.accessioned 2018-08-27T11:14:07Z
dc.date.available 2018-08-27T11:14:07Z
dc.date.issued 2011 pl
dc.identifier.issn 1733-134X pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/56461
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/pl/legalcode *
dc.title Computed tomography perfusion examination is helpful in evaluating the extent of oropharyngeal and oral cavity cancer pl
dc.type JournalArticle pl
dc.description.physical 14-19 pl
dc.description.additional Bibliogr. s. 19 pl
dc.identifier.weblink http://archiwum.polradiol.com/abstract/index/idArt/881404 pl
dc.abstract.en Background: Squamous cell cancer (SCC) of the head and neck, like other malignancies, should be reported with regard to TNM classification and treated accordingly. Sole anatomic imaging has its drawbacks, as early lesion detection often remains challenging, non-neoplastic processes can mimic malignancies and there are doubts concerning the extent of tumour. The purpose of this study was to perform assessment of head and neck squamous cell cancer and surrounding tissue, in order to examine the relationship between perfusion measurements derived from CT perfusion imaging (CTP) and histologic evaluation of resected tissue. Material/Methods: We prospectively evaluated 21 primary SCC of the oral cavity and oropharynx, using contrast enhanced CT of the head and neck followed by CTP examination at the level of tumour. Blood flow (BF), blood volume (BV), mean transit time (MTT), and permeability (PS) values were calculated with use of manually drawn regions of interest (ROIs) over the lesions and on the contralateral side. Results were compared with histologic analysis of resected tissue. Results: CTP was possible in all twenty one patients, but one did not undergo surgery. Of the remaining twenty, four had retromolar trigone cancer, nine had tongue cancer and seven had tonsil cancer. We found significant differences between infiltrated and healthy tissue. Differentiation was most reliable by using blood flow (BF), permeability surface (PS) and blood volume (BV). Conclusions: CTP shows promise in distinguishing benign and malignant processes, primarily by means of BF, BV and PS. pl
dc.subject.en squamous cell cancer pl
dc.subject.en oropharyngeal cancer pl
dc.subject.en CT perfusion pl
dc.subject.en functional imaging pl
dc.description.volume 76 pl
dc.description.number 1 pl
dc.identifier.eissn 1899-0967 pl
dc.title.journal Polish Journal of Radiology pl
dc.language.container eng pl
dc.date.accession 2018-08-27 pl
dc.subtype Article pl
dc.identifier.articleid 881404 pl
dc.rights.original CC-BY-NC-ND; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl
dc.identifier.project ROD UJ / OP pl


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 4.0 Międzynarodowa