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Chest adipose tissue distribution in patients with morbid obesity

Chest adipose tissue distribution in patients with ...

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dc.contributor.author Lemanowicz, Adam pl
dc.contributor.author Leszczyński, Waldemar pl
dc.contributor.author Rusak, Grażyna pl
dc.contributor.author Białecki, Marcin pl
dc.contributor.author Ratajczak, Przemysław pl
dc.date.accessioned 2018-02-13T07:06:12Z
dc.date.available 2018-02-13T07:06:12Z
dc.date.issued 2018 pl
dc.identifier.issn 1733-134X pl
dc.identifier.uri https://ruj.uj.edu.pl/xmlui/handle/item/50160
dc.language eng pl
dc.rights Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/pl/legalcode *
dc.title Chest adipose tissue distribution in patients with morbid obesity pl
dc.type JournalArticle pl
dc.description.physical e68-e75 pl
dc.description.additional Bibliogr. s. e74-e75 pl
dc.abstract.en Purpose: Obesity is a well-known of risk factor for atherosclerosis and the amount of visceral adipose tissue is considered as an independent predictor of coronary artery disease (CAD). An aim of the study was to investigate the distribution of intrathoracic adipose tissue in morbidly obese patients. Material and methods: Fifty-one patients with morbid obesity (BMI ≥ 40 kg/m2) and thirty controls were scanned in a coronary calcium scoring protocol. Control group consisted of patients scanned due to a clinical suspicion of CAD, who did not fulfill obesity criteria. The amount of adipose tissue was measured as epicardial adipose tissue (EAT) thickness, pericoronary fat (PCF) thickness, total intra-pericardial fat (IPF) volume, and total intrathoracic fat (ITF) volume. Results: Mean BMI of obese patients and controls was 47.3 and 26.5, respectively (p < 0.0001). Patients with obesity and controls did not differ with respect to mean EAT, mean PCF, and IPF. However, ITF was lower in obesity group than in control group (268 vs. 332 cm3, respectively; p < 0.03). Moreover, ROC analysis presented relation between obesity and the superior EAT thickness, PCF at LCX, mean PCF, ITF, and chest soft tissue (CST) thickness (p < 0.03). CST thickness of > 60 mm was the parameter that presented the strongest association with morbid obesity (AUC 0.95; p < 0.0001). Conlcusions: Increased chest soft tissue thickness but not the increased intrathoracic adipose tissue volume was associated with morbid obesity. Since the quantity of the pericardiac fat is not directly related to the obesity, its accumulation may be related to a mechanism different than that of subcutaneous adipose tissue growth. pl
dc.subject.en adipose tissue pl
dc.subject.en multidetector computed tomography pl
dc.subject.en obesity pl
dc.subject.en morbid pl
dc.description.volume 83 pl
dc.identifier.doi 10.5114/pjr.2018.73406 pl
dc.identifier.eissn 1899-0967 pl
dc.title.journal Polish Journal of Radiology pl
dc.language.container eng pl
dc.subtype Article pl
dc.rights.original CC-BY-NC-ND; otwarte czasopismo; ostateczna wersja wydawcy; w momencie opublikowania; 0 pl


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Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska Except where otherwise noted, this item's license is described as Udzielam licencji. Uznanie autorstwa - Użycie niekomercyjne - Bez utworów zależnych 3.0 Polska